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Case Reports
. 2023 Dec 21;16(12):e253883.
doi: 10.1136/bcr-2022-253883.

Felbamate urolithiasis

Ilana Bergelson  1 , Chance Walker  2   3 , Elizabeth L Frank  3   4 , Ryan Steinberg  5
Affiliations
Case Reports

Felbamate urolithiasis

Ilana Bergelson et al. BMJ Case Rep. .

Abstract

Drug-induced nephrolithiasis is an important consideration in recurrent stone formers with polypharmacy. While felbamate nephrolithiasis has previously been published in the paediatric population, we present the oldest published case of a felbamate stone in an adult, a man in his 30s with Lennox-Gastaut syndrome. Even with moderate dosing, high drug serum levels can occur. Performing at least one stone analysis remains a critical component to care in these patients. Urologists should have a high index of suspicion for drug stone when stone analysis returns indeterminate characterisation in the absence of infection. Close communication with neurology is key to preventing recurrent stone disease.

Keywords: Epilepsy and seizures; Urological surgery.

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Conflict of interest statement

Competing interests: None declared.

References

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