HER destiny too
- PMID: 38130308
- PMCID: PMC10731343
- DOI: 10.21037/tcr-23-1431
HER destiny too
Keywords: Destiny; trastuzumab deruxtecan (T-DXd); trastuzumab emtansine (T-DM1).
Conflict of interest statement
Conflicts of Interest: The author has completed the ICMJE uniform disclosure form (available at https://tcr.amegroups.com/article/view/10.21037/tcr-23-1431/coif). The author has no conflicts of interest to declare.
Comment on
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Trastuzumab deruxtecan versus treatment of physician's choice in patients with HER2-positive metastatic breast cancer (DESTINY-Breast02): a randomised, open-label, multicentre, phase 3 trial.Lancet. 2023 May 27;401(10390):1773-1785. doi: 10.1016/S0140-6736(23)00725-0. Epub 2023 Apr 20. Lancet. 2023. PMID: 37086745 Clinical Trial.
References
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- Doi T, Shitara K, Naito Y, et al. Safety, pharmacokinetics, and antitumour activity of trastuzumab deruxtecan (DS-8201), a HER2-targeting antibody-drug conjugate, in patients with advanced breast and gastric or gastro-oesophageal tumours: a phase 1 dose-escalation study. Lancet Oncol 2017;18:1512-22. 10.1016/S1470-2045(17)30604-6 - DOI - PubMed
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