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Editorial
. 2023 Dec 7;29(45):5945-5952.
doi: 10.3748/wjg.v29.i45.5945.

Gut microbiota in women: The secret of psychological and physical well-being

Affiliations
Editorial

Gut microbiota in women: The secret of psychological and physical well-being

Giuseppe Marano et al. World J Gastroenterol. .

Abstract

The gut microbiota works in unison with the host, promoting its health. In particular, it has been shown to exert protective, metabolic and structural functions. Recent evidence has revealed the influence of the gut microbiota on other organs such as the central nervous system, cardiovascular and the endocrine-metabolic systems and the digestive system. The study of the gut microbiota is outlining new and broader frontiers every day and holds enormous innovation potential for the medical and pharmaceutical fields. Prevention and treatment of specific women's diseases involves the need to deepen the function of the gut as a junction organ where certain positive bacteria can be very beneficial to health. The gut microbiota is unique and dynamic at the same time, subject to external factors that can change it, and is capable of modulating itself at different stages of a woman's life, playing an important role that arises from the intertwining of biological mechanisms between the microbiota and the female genital system. The gut microbiota could play a key role in personalized medicine.

Keywords: Gut microbiota; Gut-brain axis; Health promotion; Immune system; Metabolites; Women.

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Conflict of interest statement

Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.

Figures

Figure 1
Figure 1
Gut-brain axis interaction.
Figure 2
Figure 2
Interplay between maternal and fetal microbiota.

References

    1. Kennedy MS, Chang EB. The microbiome: Composition and locations. Prog Mol Biol Transl Sci. 2020;176:1–42. - PMC - PubMed
    1. Human Microbiome Project Consortium. Structure, function and diversity of the healthy human microbiome. Nature. 2012;486:207–214. - PMC - PubMed
    1. Marano G, Mazza M, Lisci FM, Ciliberto M, Traversi G, Kotzalidis GD, De Berardis D, Laterza L, Sani G, Gasbarrini A, Gaetani E. The Microbiota-Gut-Brain Axis: Psychoneuroimmunological Insights. Nutrients. 2023;15 - PMC - PubMed
    1. Garg S, Sharma N, Bharmjeet, Das A. Unraveling the intricate relationship: Influence of microbiome on the host immune system in carcinogenesis. Cancer Rep (Hoboken) 2023:e1892. - PMC - PubMed
    1. Hamjane N, Mechita MB, Nourouti NG, Barakat A. Gut microbiota dysbiosis -associated obesity and its involvement in cardiovascular diseases and type 2 diabetes. A systematic review. Microvasc Res. 2023;151:104601. - PubMed

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