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Review
. 2023 Dec 14;12(12):1733.
doi: 10.3390/antibiotics12121733.

How We Treat Drug-Susceptible Pulmonary Tuberculosis: A Practical Guide for Clinicians

Niccolò Riccardi  1   2 , Sara Occhineri  1   2 , Elisa Vanino  1   3 , Roberta Maria Antonello  1 , Agostina Pontarelli  1   4 , Francesca Saluzzo  1   5 , Tiziana Masini  1 , Giorgio Besozzi  1 , Marina Tadolini  1   6   7 , Luigi Codecasa  1   8 , On Behalf Of StopTB Italia
Affiliations
Review

How We Treat Drug-Susceptible Pulmonary Tuberculosis: A Practical Guide for Clinicians

Niccolò Riccardi et al. Antibiotics (Basel). .

Abstract

Tuberculosis (TB) remains one of the leading causes of morbidity and mortality worldwide and pulmonary TB (PTB) is the main variant responsible for fueling transmission of the infection. Effective treatment of drug-susceptible (DS) TB is crucial to avoid the emergence of Mycobacterium tuberculosis-resistant strains. In this narrative review, through a fictional suggestive case of DS PTB, we guide the reader in a step-by-step commentary to provide an updated review of current evidence in the management of TB, from diagnosis to post-treatment follow-up. World Health Organization and Centre for Diseases Control (CDC) guidelines for TB, as well as the updated literature, were used to support this manuscript.

Keywords: diagnosis; drug susceptible; pulmonary TB; treatment; tuberculosis.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Chest CT scan at presentation (Panel (A–F)).
Figure 2
Figure 2
Chest CT scan at the end of treatment (Panel (A–F)).
Figure 3
Figure 3
The goals of effective TB care for patients with DS-PTB.
See this image and copyright information in PMC

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