Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Dec 1;11(12):3200.
doi: 10.3390/biomedicines11123200.

Equilibrium Optimization Algorithm with Deep Learning Enabled Prostate Cancer Detection on MRI Images

Affiliations

Equilibrium Optimization Algorithm with Deep Learning Enabled Prostate Cancer Detection on MRI Images

Eunmok Yang et al. Biomedicines. .

Abstract

The enlargement of the prostate gland in the reproductive system of males is considered a form of prostate cancer (PrC). The survival rate is considerably improved with earlier diagnosis of cancer; thus, timely intervention should be administered. In this study, a new automatic approach combining several deep learning (DL) techniques was introduced to detect PrC from MRI and ultrasound (US) images. Furthermore, the presented method describes why a certain decision was made given the input MRI or US images. Many pretrained custom-developed layers were added to the pretrained model and employed in the dataset. The study presents an Equilibrium Optimization Algorithm with Deep Learning-based Prostate Cancer Detection and Classification (EOADL-PCDC) technique on MRIs. The main goal of the EOADL-PCDC method lies in the detection and classification of PrC. To achieve this, the EOADL-PCDC technique applies image preprocessing to improve the image quality. In addition, the EOADL-PCDC technique follows the CapsNet (capsule network) model for the feature extraction model. The EOA is based on hyperparameter tuning used to increase the efficiency of CapsNet. The EOADL-PCDC algorithm makes use of the stacked bidirectional long short-term memory (SBiLSTM) model for prostate cancer classification. A comprehensive set of simulations of the EOADL-PCDC algorithm was tested on the benchmark MRI dataset. The experimental outcome revealed the superior performance of the EOADL-PCDC approach over existing methods in terms of different metrics.

Keywords: cancer diagnosis; deep learning; equilibrium optimizer; magnetic resonance imaging; prostate cancer.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
The overall working flow of the EOADL-PCDC technique.
Figure 2
Figure 2
BiLSTM structure.
Figure 3
Figure 3
Confusion matrices of (a,b) 80% of TRAP/20% of TESP and (c,d) 70% of TRAP/30% of TESP.
Figure 4
Figure 4
Average of the EOADL-PCDC system on 80:20 of TRAP/TESP.
Figure 5
Figure 5
Accuy curve of the EOADL-PCDC algorithm on 80:20 of TRAP/TESP.
Figure 6
Figure 6
Loss curve of the EOADL-PCDC system on 80:20 of TRAP/TESP.
Figure 7
Figure 7
PR analysis of EOADL-PCDC technique on 80:20 of TRAP/TESP.
Figure 8
Figure 8
ROC analysis of the EOADL-PCDC technique on 80:20 of TRAP/TESP.
Figure 9
Figure 9
Average of the EOADL-PCDC method on 70:30 of TRAP/TESP.
Figure 10
Figure 10
Accuy curve of the EOADL-PCDC technique on 70:30 of TRAP/TESP.
Figure 11
Figure 11
Loss curve of the EOADL-PCDC technique on 70:30 of TRAP/TESP.
Figure 12
Figure 12
PR curve of the EOADL-PCDC algorithm on 70:30 of TRAP/TESP.
Figure 13
Figure 13
ROC curve of the EOADL-PCDC model on 70:30 of TRAP/TESP.
Figure 14
Figure 14
Comparative outcome of the EOADL-PCDC algorithm with recent systems.

References

    1. Hamm C.A., Baumgärtner G.L., Biessmann F., Beetz N.L., Hartenstein A., Savic L.J., Froböse K., Dräger F., Schallenberg S., Rudolph M., et al. Interactive Explainable Deep Learning Model Informs Prostate Cancer Diagnosis at MRI. Radiology. 2023;307:e222276. doi: 10.1148/radiol.222276. - DOI - PubMed
    1. Bosma J.S., Saha A., Hosseinzadeh M., Slootweg I., de Rooij M., Huisman H. Annotation-efficient cancer detection with report-guided lesion annotation for deep learning-based prostate cancer detection in bpMRI. arXiv. 20212112.05151 - PMC - PubMed
    1. Mehralivand S., Yang D., Harmon S.A., Xu D., Xu Z., Roth H., Masoudi S., Kesani D., Lay N., Merino M.J. Deep learning-based artificial intelligence for prostate cancer detection at biparametric MRI. Abdom. Radiol. 2022;47:1425–1434. doi: 10.1007/s00261-022-03419-2. - DOI - PMC - PubMed
    1. Bosma J.S., Saha A., Hosseinzadeh M., Slootweg I., de Rooij M., Huisman H. Semi-supervised Learning with Report-guided Pseudo Labels for Deep Learning-based Prostate Cancer Detection Using Biparametric MRI. Radiol. Artif. Intell. 2023;5:e230031. doi: 10.1148/ryai.230031. - DOI - PMC - PubMed
    1. Li D., Han X., Gao J., Zhang Q., Yang H., Liao S., Guo H., Zhang B. Deep learning in prostate cancer diagnosis using multiparametric magnetic resonance imaging with whole-mount histopathology referenced delineations. Front. Med. 2022;8:810995. doi: 10.3389/fmed.2021.810995. - DOI - PMC - PubMed

LinkOut - more resources