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Review
. 2023 Dec 13;12(24):7644.
doi: 10.3390/jcm12247644.

The Evaluation and Management of Coronary Artery Disease in the Lung Transplant Patient

Gregory Serrao  1 , Manish Vinayak  1 , Johny Nicolas  1 , Varsha Subramaniam  1 , Ashton C Lai  1 , Daniel Laskey  1 , Annapoorna Kini  1 , Harish Seethamraju  1 , Scott Scheinin  1
Affiliations
Review

The Evaluation and Management of Coronary Artery Disease in the Lung Transplant Patient

Gregory Serrao et al. J Clin Med. .

Abstract

Lung transplantation can greatly improve quality of life and extend survival in those with end-stage lung disease. In order to derive the maximal benefit from such a procedure, patients must be carefully selected and be otherwise healthy enough to survive a high-risk surgery and sometimes prolonged immunosuppressive therapy following surgery. Patients therefore must be critically assessed prior to being listed for transplantation with close attention paid towards assessment of cardiovascular health and operative risk. One of the biggest dictators of this is coronary artery disease. In this review article, we discuss the assessment and management of coronary artery disease in the potential lung transplant candidate.

Keywords: coronary artery bypass surgery; coronary artery disease; lung transplant evaluation; percutaneous coronary intervention.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Common risk factors for coronary artery disease and lung disease.
Figure 2
Figure 2
Medical management of coronary artery disease in lung transplant candidates.
Figure 3
Figure 3
Proposed algorithm for protocolized assessment of coronary artery disease in lung transplant candidates. #: Two or more risk factors for cardiovascular disease (CVD): dyslipidemia, diabetes, hypertension, smoking, family history of CVD, prior established CVD. *: One or more clinical risk factor according to the Revised Cardiac Risk Index (RCRI): ischemic heart disease, cerebrovascular disease, history of congestive heart failure, serum creatinine level > 2 mg/dl, diabetes requiring insulin therapy. CABG: Coronary Artery Bypass Grafting, CCTA: Coronary Computed Tomography Angiography, CMR: Cardiac Magnetic Resonance, DSE: Dobutamine Stress Echocardiogram, ECG: Electrocardiogram, iFR: instantaneous wave-free pressure ratio, PCI: Percutaneous Coronary Intervention, PET: Positron Emission Tomography, SPECT-MPI: Single Positron Emission Tomography-Myocardial Perfusion Imaging, TTE: Trans-Thoracic Echocardiogram.
See this image and copyright information in PMC

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