Case Reports
Ultrastructural abnormalities of the liver in total lipodystrophy
- PMID: 3813836
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Case Reports
Ultrastructural abnormalities of the liver in total lipodystrophy
Arch Pathol Lab Med.
1987 Feb.
Abstract
We present the results of light and electron microscopy studies of the liver in an 8-year-old girl with congenital total lipodystrophy. Liver histology revealed cirrhosis, and ultrastructural study showed mitochondrial abnormalities and an increase in the number of peroxisomes. A potential relationship between the high fatty acid concentration in the serum and the peroxisomal proliferation is considered.
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