Vaccination for Respiratory Syncytial Virus: A Narrative Review and Primer for Clinicians
- PMID: 38140213
- PMCID: PMC10747850
- DOI: 10.3390/vaccines11121809
Vaccination for Respiratory Syncytial Virus: A Narrative Review and Primer for Clinicians
Abstract
Respiratory syncytial virus (RSV) poses a significant burden on public health, causing lower respiratory tract infections in infants, young children, older adults, and immunocompromised individuals. Recent development and licensure of effective RSV vaccines provide a promising approach to lessening the associated morbidity and mortality of severe infections. This narrative review aims to empower clinicians with the necessary knowledge to make informed decisions regarding RSV vaccination, focusing on the prevention and control of RSV infections, especially among vulnerable populations. The paper explores the available RSV vaccines and existing evidence regarding their efficacy and safety in diverse populations. Synthesizing this information for clinicians can help the latter understand the benefits and considerations associated with RSV vaccination, contributing to improved patient care and public health outcomes.
Keywords: adjuvants; immunologic; mRNA vaccines; pneumonia; vaccination hesitancy; viral; viral fusion proteins.
Conflict of interest statement
The author declares honoraria for talks sponsored by AstraZeneca plc, GSK Inc. Moderna Inc., and Pfizer Inc.
References
-
- Chanock R., Roizman B., Myers R. Recovery from Infants with Respiratory Illness of a Virus Related to Chimpanzee Coryza Agent (Cca). I. Isolation, Properties and Characterization. Am. J. Hyg. 1957;66:281–290. - PubMed
-
- Chanock R., Finberg L. Recovery from Infants with Respiratory Illness of a Virus Related to Chimpanzee Coryza Agent (Cca). II. Epidemiologic Aspects of Infection in Infants and Young Children. Am. J. Hyg. 1957;66:291–300. - PubMed
-
- Li Y., Wang X., Blau D.M., Caballero M.T., Feikin D.R., Gill C.J., Madhi S.A., Omer S.B., Simoes E.A.F., Campbell H., et al. Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in children younger than 5 years in 2019: A systematic analysis. Lancet. 2022;399:2047–2064. doi: 10.1016/S0140-6736(22)00478-0. - DOI - PMC - PubMed
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