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. 1986 Dec 1;240(2):605-7.
doi: 10.1042/bj2400605.

Olfactory adenylate cyclase of the rat. Stimulation by odorants and inhibition by Ca2+

S G Shirley, C J Robinson, K Dickinson, R Aujla, G H Dodd

Olfactory adenylate cyclase of the rat. Stimulation by odorants and inhibition by Ca2+

S G Shirley et al. Biochem J. .

Abstract

Membranes prepared from the olfactory mucosa of the rat show a high level of adenylate cyclase activity. The activity increases up to 2-fold in the presence of physiologically relevant concentrations of odorants and is inhibited by Ca2+. The level of cyclase activity found is sufficient to explain the speed of olfactory transduction, which occurs on a time scale of tens of milliseconds.

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