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Case Reports
. 2023 Nov 30;15(11):e49749.
doi: 10.7759/cureus.49749. eCollection 2023 Nov.

Anesthetic Challenge in a Parturient With Von Hippel-Lindau Disease

Siyu Lye  1 , Angie Phui Sze Au Yong  1
Affiliations
Case Reports

Anesthetic Challenge in a Parturient With Von Hippel-Lindau Disease

Siyu Lye et al. Cureus. .

Abstract

Von Hippel-Lindau (VHL) syndrome is a rare autosomal dominant disease with incomplete penetrance and variable expression. The features of cerebellar and spinal tumors, pheochromocytomas, and increased intracranial pressure complicate the anesthetic management of such patients. This report describes the anesthetic management of a parturient with VHL disease and highlights the importance of proper surveillance, vigilant management, and individualized treatment plans from a multidisciplinary team.

Keywords: anesthesia; central neuraxial blockade; epidural; obstetrics; von hippel-lindau syndrome.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Surveillance MRI of the brain done at 20 weeks gestation, showing stable hemangioma (0.3 cm) in the cerebellar with no new mass and no features of increased intracranial pressure.
See this image and copyright information in PMC

References

    1. Prevalence, birth incidence, and penetrance of von Hippel-Lindau disease (vHL) in Denmark. Binderup ML, Galanakis M, Budtz-Jørgensen E, Kosteljanetz M, Luise Bisgaard M. Eur J Hum Genet. 2017;25:301–307. - PMC - PubMed
    1. von Hippel-Lindau disease: updated guideline for diagnosis and surveillance. Louise M Binderup M, Smerdel M, Borgwadt L, et al. Eur J Med Genet. 2022;65:104538. - PubMed
    1. von Hippel-Lindau disease and pregnancy: what an obstetrician should know. Adekola H, Soto E, Lam J, Bronshtein E, Chaiworapongsa T, Sorokin Y. Obstet Gynecol Surv. 2013;68:655–662. - PubMed
    1. Survival and causes of death in patients with von Hippel-Lindau disease. Binderup ML, Jensen AM, Budtz-Jørgensen E, Bisgaard ML. J Med Genet. 2017;54:11–18. - PubMed
    1. "Active labor" duration and dilation rates among low-risk, nulliparous women with spontaneous labor onset: a systematic review. Neal JL, Lowe NK, Ahijevych KL, Patrick TE, Cabbage LA, Corwin EJ. J Midwifery Womens Health. 2010;55:308–318. - PMC - PubMed

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