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. 2024 Feb 7;45(2):183-187.
doi: 10.3174/ajnr.A8093.

Discrimination of Hemorrhage and Contrast Media in a Head Phantom on Photon-Counting Detector CT Data

Franka Risch  1 , Ansgar Berlis  2 , Thomas Kroencke  1   3 , Florian Schwarz  1   4 , Christoph J Maurer  5
Affiliations

Discrimination of Hemorrhage and Contrast Media in a Head Phantom on Photon-Counting Detector CT Data

Franka Risch et al. AJNR Am J Neuroradiol. .

Abstract

In this anthropomorphic head phantom study, samples containing blood and contrast agent with concentrations ranging from 0 to 6 mg iodine per milliliter and another set of samples without blood for reference were scanned with a photon-counting detector CT using a standard cranial protocol. It was demonstrated that photon-counting detector CT can reliably distinguish hemorrhage and contrast media, including density determination of the latter. The technology promises to add value in several neuroimaging applications.

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Figures

FIG 1.
FIG 1.
The schematic structure of the phantom and the respective positions of measurement. A indicates anterior; C, central; L, left; Rposterior, posterior reference; Rright, right reference).
FIG 2.
FIG 2.
Measured CT values within the samples without (A) and with (B) blood, at all positions (anterior, center, left) and on all slices (next and above the temporal bone structures) presented in boxplots. CT values are compared among ME70, the CM map, and VNC. Statistically significant differences are marked. n.s. indicates P > . 05; *, P < . 05; **, P < . 01; ***, P < . 001).
FIG 3.
FIG 3.
Linear regression of initial and measured iodine concentration of the samples. Reference samples without (A) and with (B) blood including all positions (anterior, center, left) and the compared between-sections above and next to temporal bone (tb) structures.
FIG 4.
FIG 4.
Bland-Altman plots showing the means and differences between the measured and actual iodine concentrations in samples without (A) and with (B) blood. All positions (anterior, center, and left) and sections (above and next to temporal bone structures) are considered. W/o indicates without; w, with.
See this image and copyright information in PMC

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