Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2023 Dec;5(6):e230165.
doi: 10.1148/ryct.230165.

Filamin C-associated Cardiomyopathy on Cardiac MR Images

Affiliations
Case Reports

Filamin C-associated Cardiomyopathy on Cardiac MR Images

Segolene Weller et al. Radiol Cardiothorac Imaging. 2023 Dec.
No abstract available

Keywords: Cardiac MRI; Cardiomyopathy; Filamin C; MR Imaging.

PubMed Disclaimer

Conflict of interest statement

Disclosures of conflicts of interest: S.W. No relevant relationships. C.B.O. No relevant relationships. C.F. Grant from the National Institutes of Health; royalties from Elsevier and Siemens Healthineers; payment for the Society of Cardiovascular Computed Tomography Board Review; travel support from the Society of Cardiovascular Computed Tomography; member of the Society of Cardiovascular Computed Tomography Board of Directors; spouse owns stock in ViewRay; associate editor for Radiology: Cardiothoracic Imaging. E.H.W. No relevant relationships.

Figures

Cardiac MR images in a 21-year-old male patient with filamin C
variant–associated cardiomyopathy. Postcontrast T1-weighted images acquired
with a 1.5-T MRI scanner in (A) short-axis view and (B) vertical long-axis view
demonstrate marked concentric (or “ringlike”) midmyocardial late
gadolinium enhancement of the left ventricle (yellow arrows). (C) Native T1 mapping
image in short-axis view demonstrates an elevated T1 value (1120 msec).
Cardiac MR images in a 21-year-old male patient with filamin C variant–associated cardiomyopathy. Postcontrast T1-weighted images acquired with a 1.5-T MRI scanner in (A) short-axis view and (B) vertical long-axis view demonstrate marked concentric (or “ringlike”) midmyocardial late gadolinium enhancement of the left ventricle (yellow arrows). (C) Native T1 mapping image in short-axis view demonstrates an elevated T1 value (1120 msec).

References

    1. Ortiz-Genga MF , Cuenca S , Dal Ferro M , et al. . Truncating FLNC Mutations Are Associated With High-Risk Dilated and Arrhythmogenic Cardiomyopathies . J Am Coll Cardiol 2016. ; 68 ( 22 ): 2440 – 2451 . - PubMed
    1. Augusto JB , Eiros R , Nakou E , et al. . Dilated cardiomyopathy and arrhythmogenic left ventricular cardiomyopathy: a comprehensive genotype-imaging phenotype study . Eur Heart J Cardiovasc Imaging 2020. ; 21 ( 3 ): 326 – 336 . - PubMed
    1. Wang H , Bo K , Gao Y , Zhou Z , Xu L . Prognosis evaluation of chronic inflammatory cardiomyopathy with ring-like late gadolinium enhancement . ESC Heart Fail 2023. ; 10 ( 3 ): 1735 – 1744 . - PMC - PubMed