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. 2022 Nov 3;48(11-12):522-528.
doi: 10.14745/ccdr.v48i1112a05.

Overview of Canada's Antimicrobial Resistance Network (AMRNet): A data-driven One Health approach to antimicrobial resistance surveillance

Wallis Rudnick  1 , Shamir N Mukhi  2 , Richard J Reid-Smith  3 , Greg J German  4 , Anil Nichani  5 , Michael R Mulvey  6 ; Canadian Public Health Laboratory Network Antimicrobial Resistance Working Group; Canadian Animal Health Laboratorians Network Antimicrobial Susceptibility Testing Working Group
Affiliations

Overview of Canada's Antimicrobial Resistance Network (AMRNet): A data-driven One Health approach to antimicrobial resistance surveillance

Wallis Rudnick et al. Can Commun Dis Rep. .

Abstract

The Antimicrobial Resistance Network (AMRNet) is a laboratory-based antimicrobial resistance (AMR) surveillance system under development at the Public Health Agency of Canada's (PHAC's) National Microbiology Laboratory. The AMRNet surveillance system captures information on antimicrobial susceptibility testing from clinical and veterinary laboratories including both public and private facilities. In the future, the AMRNet system will also capture relevant data from existing PHAC surveillance systems for AMR including the Canadian Integrated Program for Antimicrobial Resistance Surveillance, the Canadian Nosocomial Infection Surveillance Program and the Enhanced Surveillance of Antimicrobial-Resistant Gonorrhea program, and contribute to the Canadian Antimicrobial Resistance Surveillance System. AMRNet's integrated "One Health" approach will allow health professionals and researchers to take a multi-dimensional perspective of AMR in both human and animal health in Canada and will make Canada a leader in AMR surveillance. AMRNet is a collaboration between PHAC, provincial and territorial public health organizations as well as clinical and veterinary laboratories across the country. As part of a phased rollout, AMRNet is now collecting human clinical data from three provinces, from both inpatients and outpatients. Ultimately, AMRNet aims to capture all antimicrobial susceptibility testing results from all bacterial and fungal pathogens across Canada. This article describes the AMRNet surveillance system, including program objectives, system structure and the data collected. The integration of human and animal data in AMRNet will inform One Health responses to AMR issues. The capacity to collect and to disseminate data to stakeholders in real time is a critical step to addressing emerging AMR issues in Canada.

Keywords: Antimicrobial Resistance Network; antimicrobial resistance; antimicrobial susceptibility; bacteria; fungi; one health; surveillance.

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Conflict of interest statement

Competing interests None.

Figures

Figure 1
Figure 1
Data flow for AMRNet surveillance system Abbreviations: AMR, antimicrobial resistance; AMRNet, Antimicrobial Resistance Network; PHAC, Public Health Agency of Canada a Laboratories funded, managed or operated by governmental health organizations b AMRNet is currently conducting surveillance among veterinary laboratories as a pilot program
Figure 2
Figure 2
High-level depiction of the technical vision behind the AMRNet initiative on the Canadian Network for Public Health Intelligence platform Abbreviations: AMRNet, Antimicrobial Resistance Network; CNPHI, Canadian Network for Public Health Intelligence
See this image and copyright information in PMC

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