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Review
. 2024 Sep;196(9):5740-5764.
doi: 10.1007/s12010-023-04835-w. Epub 2024 Jan 5.

Recent Progress on Peroxidase Modification and Application

Chen Shen  1   2 , Yongfa Wang  3
Affiliations
Review

Recent Progress on Peroxidase Modification and Application

Chen Shen et al. Appl Biochem Biotechnol. 2024 Sep.

Abstract

Peroxdiase is one of the member of oxireductase super family, which has a broad substrate range and a variety of reaction types, including hydroxylation, epoxidation or halogenation of unactivated C-H bonds, and aromatic group or biophenol compounds. Here, we summarized the recently discovered enzymes with peroxidation activity, and focused on the special structures, sites, and corresponding strategies that can change the peroxidase catalytic activity, stability, and substrate range. The comparison of the structural differences between these natural enzymes and the mimic enzymes of binding nanomaterials and polymer materials is helpful to expand the application of peroxidase in industry. In addition, we also reviewed the catalytic application of peroxidase in the synthesis of important organic molecules and the degradation of pollutants.

Keywords: Biological oxidation; Chemical synthesis; Fungal enzyme; Lignin; Peroxidase.

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Conflict of interest statement

Declarations. Ethical Approval: Not applicable. Consent to Participate: Not applicable. Consent for Publication: Not applicable. Competing Interests: The authors declare no competing interests.

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