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Randomized Controlled Trial
. 2024 May 1;44(5):764-773.
doi: 10.1097/IAE.0000000000004026.

LASER FLARE PHOTOMETRY IN PRIMARY RHEGMATOGENOUS RETINAL DETACHMENT: An Evaluation of 2,487 Cases

Caroline Gietzelt  1 , Robert Hoerster  2 , Petra Schiller  3 , Saskia Hermann  1 , Daria Kraus  4 , Frank G Holz  5 , Rainer Guthoff  6 , Hansjürgen Agostini  7 , Martin S Spitzer  8 , Peter Wiedemann  9 , Albrecht Lommatzsch  10 , Karl T Boden  11 , Ulrich Bartz-Schmidt  12 , Sebastian Bemme  13 , Svenja Tamm  14 , Mathias Maier  15 , Johann Roider  16 , Bernd Kirchhof  1 , Sascha Fauser  17 , Friederike Schaub  1   18 ; PRIVENT Study Group
Collaborators, Affiliations
Randomized Controlled Trial

LASER FLARE PHOTOMETRY IN PRIMARY RHEGMATOGENOUS RETINAL DETACHMENT: An Evaluation of 2,487 Cases

Caroline Gietzelt et al. Retina. .

Abstract

Purpose: Exploratory analysis associated with the prospective, multicenter, randomized PRIVENT trial. To characterize the associations between laser flare photometry and anatomical and epidemiological features of rhegmatogenous retinal detachment (RRD).

Methods: The authors measured laser flare values of all 3,048 prescreened patients excluding those with comorbidities. A mixed regression analysis evaluated the strength of the influencing factors like age, sex, lens status, and presence and extent of RRD on laser flare.

Results: Rhegmatogenous retinal detachment was more frequent in men (65.8%) than in women (34.2%, P < 0.001) and in right (52%) than in left eyes (48%, P = 0.045). Phakic RRD affected less quadrants and was less likely to be associated with macula-off status than pseudophakic RRD (48.4% vs. 58.0% macula off, 23% vs. 31% ≥3 quadrants, P < 0.001). Laser flare of affected eyes was significantly higher compared with fellow eyes (12.6 ± 15.2 vs. 8.3 ± 7.4 pc/ms, P < 0.001). The factors age, sex, lens status, presence of RRD, and the number of quadrants affected were independent influencing factors on laser flare. R 2 was 0.145 for phakic and 0.094 for pseudophakic eyes.

Conclusion: The results indicate that there may be more factors affecting laser flare than previously assumed. This might limit flare as predictive value for PVR and retinal redetachment.

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References

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