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Comment
. 2024 Jan 4;31(1):5-6.
doi: 10.1016/j.stem.2023.12.005.

Scaling up GMP-grade dopaminergic cells for Parkinson's disease

Thomas Foltynie  1
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Scaling up GMP-grade dopaminergic cells for Parkinson's disease

Thomas Foltynie. Cell Stem Cell. .
Free article

Abstract

Stem cell therapy for Parkinson's disease requires demonstration of safety and efficacy of dopaminergic cells derived from a cell line, consideration of dose, and whether this is deliverable at scale. Park et al. demonstrate these requirements for a new hESC line and that their manufacturing methods allow for its scalability.

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Conflict of interest statement

Declaration of interests T.F. has served on advisory boards for Peptron, Voyager Therapeutics, Handl therapeutics, Gain therapeutics, Living Cell Technologies, Abbvie, Bluerock, Bayer, Novo Nordisk, and Bial.

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