Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Nov;12(11):2927-2933.
doi: 10.4103/jfmpc.jfmpc_874_23. Epub 2023 Nov 21.

Correlation of perceived stress with monthly cyclical changes in the female body

Affiliations

Correlation of perceived stress with monthly cyclical changes in the female body

Prashant Jain et al. J Family Med Prim Care. 2023 Nov.

Abstract

Background: Women are liable to stress-related disorders as female sex hormone, estrogen has been indicated to be protective against stress disorders. The hormone level varies with different phases of menstrual cycle. Moreover, postmenopausal women are at risk for stress-related disorders. So this study was done to correlate the different phases of menstrual cycle with the perceived stress in different phases of monthly cycle.

Methods: This study was conducted in the Department of Physiology, Shri Guru Ram Rai Institute of Medical and Health Sciences (SGRRIMHS), Dehradun. Four hundred girls in the age group of 18-26 years were selected for the study. The Perceived Stress Scale (PSS) questionnaire was circulated via Google forms after briefing them about the study. Informed consent was also taken. The menstrual history of the subjects was enquired by one-to-one interaction. The participants completed the PSS questionnaire twice in the same cycle. Data collected were statistically analyzed, using Independent t-test and Chi-square test and point biserial correlation test.

Result: The analysis showed strong statistical association of PSS with two phases of menstrual cycle. The PSS score was higher in the late luteal and menstrual phase, while it was less in the late follicular phase (P < 0.05). Conclusion: The decreased oestrogen levels in the late luteal & menstrual phase are strongly associated with perceived stress in our study. Hormonal changes in the monthly cycles are related with stress, behavioral shift and many other physical changes in females. This information to the family physicians would be beneficial in counseling the females regarding various changes occurring during the menstrual cycle.

Keywords: Early follicular phase; estrogen; late luteal phase; perceived stress.

PubMed Disclaimer

Conflict of interest statement

There are no conflicts of interest.

References

    1. Hall JE, Hall M. In: Textbook of Medical Physiology. 3rd. Vaz M, , Kurpad A, Raj T, , editors. Elsevier Inc.; India (South Asia): 2022. p. 693.
    1. Wang L, Wang X, Wang W, Chen C, Ronnennberg AG, Guang W, et al. Stress and dysmenorrhea: A population based prospective study. Occup Environ Med. 2004;61:1021–6. - PMC - PubMed
    1. Nagma S, Kapoor G, Bharti R, Batra A, Batra A, Aggarwal A, et al. To evaluate the effect of perceived stress on menstrual function. J Clin Diagn Res. 2015;9:QC1–3. - PMC - PubMed
    1. Gul A, Ugur M, Iskender C, Zulfikaroglu E, Ozaksit G. Immunohistochemical expression of estrogen and progesterone receptors in endometrial polyps and its relationship to clinical parameters. Arch Gynecol. 2010;281:479–83. - PubMed
    1. Chatterjee S, Aditya S, Tibarewala DN. A comparative study between females of prepubertal and reproductive age groups to explore how HPG-axis affects the autonomic control over cardiac activity. Indian J Biomech. 2009;7:233–6.