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. 2023 Dec 15;15(12):6867-6877.
eCollection 2023.

A bibliometric analysis of studies of exosomes in ischemic stroke published from 2002 to 2021

Ruihua Wang  1   2   3 , Zhang Yang  2 , Ziyang Zhou  1 , Xiaolu Yang  1 , Lan Chu  1   2
Affiliations

A bibliometric analysis of studies of exosomes in ischemic stroke published from 2002 to 2021

Ruihua Wang et al. Am J Transl Res. .

Abstract

Recently, research on exosomes in ischemic stroke has become an attractive field worldwide, and therefore the number of relevant publications has increased. The objective of the present study is to visualize the current research status and hotspots in this area by performing bibliometric analysis and helping researchers predict future research trends. Studies regarding exosomes in ischemic stroke were retrieved from the Science Citation Index-Expanded and Social Sciences Citation Index databases of the Web of Science. Knowledge maps were constructed and visualization analysis was performed using VOSviewer and CiteSpace software. In total, 504 publications (336 articles and 168 reviews) published from 2002 to 2021 were identified in this bibliometric analysis. The leading publishing countries were China and the USA, and the top collaborating institutions were Henry Ford Hospital and Oakland University. Analyses of keywords and co-cited references revealed that microRNA, biomarkers, stem cells, therapeutic effects, neurogenesis, and neurovascular plasticity were significant hotspots and emerging trends. According to the bibliometric analysis results, our study identified the research hotspots and emerging trends relevant to exosome involvement in ischemic stroke.

Keywords: CiteSpace; Ischemic stroke; VOSviewer; bibliometrics; exosomes.

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Conflict of interest statement

None.

Figures

Figure 1
Figure 1
The overview of the publications on exosomes in ischemic stroke over the past 20 years. A. Flowchart of literature selection. B. Trends of publications. C. Co-operation of countries/regions. D. Co-operation of institutions.
Figure 2
Figure 2
A. The dual-map overlay of journals related to exosomes ischemic stroke research. B. Cooperation between different authors in this research field. C. Keywords with the strongest citation bursts in this research field of exosomes in ischemic stroke from 2002 to 2021. D. Clusters map of keywords in this research field. E. Distribution of keywords according to average publication year (blue: earlier, yellow: later).
Figure 3
Figure 3
Analysis of Co-cited References on exosomes in ischemic stroke in the past two decades. A. Co-cited references map of publications on exosomes. B. Cluster Analysis of Co-cited References in ischemic stroke. C. CiteSpace visualization map of timeline view.
See this image and copyright information in PMC

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