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Case Reports
. 2024 Jan 5;12(1):e8312.
doi: 10.1002/ccr3.8312. eCollection 2024 Jan.

Graves' disease with pancytopenia: A rare case report

Affiliations
Case Reports

Graves' disease with pancytopenia: A rare case report

Neda Meftah et al. Clin Case Rep. .

Abstract

Key clinical message: In this case report we describe a patient with Grave's disease (GD) who was first diagnosed with pancytopenia and did not have any typical symptoms of GD. His hematologic abnormalities were alleviated after treatment with an anti-thyroid drug. Hence, in patients with pancytopenia, GD should also be considered.

Abstract: A variety of hematologic abnormalities can be seen in Graves' disease (GD), however; here, we describe a patient with GD and a very rare complication; pancytopenia. His hematologic abnormalities and clinical status were alleviated after treatment with an anti-thyroid drug. Hence, in patients with pancytopenia and normal bone marrow examination, GD should also be considered.

Keywords: Graves' disease; case report; pancytopenia; thyrotoxicosis.

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Conflict of interest statement

The authors do not have any conflicts of interest.

Figures

FIGURE 1
FIGURE 1
Peripheral blood smear shows mild anisocytosis with large platelet. Large platelet is shown with an arrow. (Wright‐Giemsa stain, Magnification: 100×).
FIGURE 2
FIGURE 2
(A) Bone marrow aspiration smear shows normocellular marrow and normal hematopoiesis (Wright‐Giemsa stain). (B) Bone marrow biopsy shows about 50%cellularity (H&E stain).

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References

    1. Garla VV, Abdul Salim S, Yanes‐Cardozo LL. Pancytopenia: a rare complication of Graves' disease. BMJ Case Rep. 2018;2018. - PMC - PubMed
    1. Weetman AP. Grave's disease 1835‐2002. Horm Res. 2003;59(Suppl 1):114‐118. - PubMed
    1. Brent GA. Clinical practice. Graves' Disease N Engl J Med. 2008;358(24):2594‐2605. - PubMed
    1. Fu B, He D, Geng Z, Fu X. Graves' hyperthyroidism induced pancytopenia, epilepsia and muscle weakness: a case report. Medicine (Baltimore). 2022;101(41):e31042. - PMC - PubMed
    1. Pincet L, Gorostidi F. Graves disease causing pancytopenia: case report and literature review. Clin Med Insights Case Rep. 2018;11:1179547618781090. - PMC - PubMed

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