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. 2024 Jan 8;42(1):12.
doi: 10.1007/s00345-023-04719-y.

The landscape of penile cancer research in Germany and Austria: a survey among professors in academic centers holding chair positions and results of a literature search

Semih Sarcan #  1 , Ingmar Wolff #  2 , Lukas Lusuardi  3 , Anton Kravchuk  4 , Jens Wiegland  5 , Abdulbaki Yakac  5 , Christian Thomas  5 , Maximilian Burger  6 , Christian Gilfrich  4 , Steffen Lebentrau  7   8 , Sascha Ahyai  9 , Axel Merseburger  1 , Matthias May  10
Affiliations

The landscape of penile cancer research in Germany and Austria: a survey among professors in academic centers holding chair positions and results of a literature search

Semih Sarcan et al. World J Urol. .

Abstract

Background: Research on penile cancer (PeCa) is predominantly conducted in countries with centralized treatment of PeCa-patients. In Germany and Austria (G + A), no state-regulated centralization is established, and no information is available on how PeCa-research is organized.

Methods: Current research competence in PeCa was assessed by a 36-item questionnaire sent to all chairholders of urological academic centers in G + A. Based on PubMed records, all scientific PeCa-articles of 2012-2022 from G + A were identified. Current research trends were assessed by dividing the literature search into two periods (P1: 2012-2017, P2: 2018-2022). A bibliometric analysis was supplemented.

Results: Response rate of the questionnaire was 75%, a median of 13 (IQR: 9-26) PeCa-patients/center was observed in 2021. Retrospective case series were conducted by 38.9% of participating clinics, while involvement in randomized-controlled trials was stated in 8.3% and in basic/fundamental research in 19.4%. 77.8% declared an interest in future multicenter projects. 205 PeCa-articles were identified [median impact factor: 2.77 (IQR: 0.90-4.37)]. Compared to P1, P2 showed a significant increase in the median annual publication count (29 (IQR: 13-17) vs. 15 (IQR: 19-29), p < 0.001), in multicenter studies (79.1% vs. 63.6%, p = 0.018), and in multinational studies (53% vs. 28.9%, p < 0.001); the proportion of basic/fundamental research articles significantly declined (16.5% vs. 28.9%, p = 0.041). Four of the top-5 institutions publishing PeCa-articles are academic centers. Bibliometric analyses revealed author networks, primary research areas in PeCa, and dominant journals for publications.

Conclusions: Given the lack of centralization in G + A, this analysis highlights the need for research coordination within multicenter PeCa-projects. The decline in basic/fundamental research should be effectively addressed by the allocation of funded research projects.

Keywords: Bibliometric analysis; Penile carcinoma; Penile neoplasm; Proposal for a randomized-controlled trial; Research competence; Review of the literature.

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References

    1. Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, Bray F (2021) Global Cancer Statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 Countries. A Cancer J Clin 71(3):209–249. https://doi.org/10.3322/caac.21660 - DOI
    1. Quhal F, Pradere B, Mori K, Shariat SF (2020) Volume outcome relationship in penile cancer: a systematic review. Curr Opin Urol 30(5):696–700. https://doi.org/10.1097/MOU.0000000000000803 - DOI - PubMed
    1. Williams SB, Ray-Zack MD, Hudgins HK, Oldenburg J, Trinh QD, Nguyen PL, Shore ND, Wirth MP, O’Brien T, Catto JWF (2019) Impact of centralizing care for genitourinary malignancies to high-volume providers: a systematic review. Eur Urol Oncol 2(3):265–273. https://doi.org/10.1016/j.euo.2018.10.006 - DOI - PubMed
    1. Lebentrau S, Wakileh GA, Schostak M, Schmid HP, Suarez-Ibarrola R, Merseburger AS, Hutterer GC, Necknig UH, Rink M, Bögemann M, Kluth LA, Pycha A, Burger M, Brookman-May SD, Bründl J, May M (2021) Does the identification of a minimum number of cases correlate with better adherence to international guidelines regarding the treatment of penile cancer? survey results of the European PROspective Penile Cancer Study (E-PROPS). Front Oncol 11:759362. https://doi.org/10.3389/fonc.2021.759362 - DOI - PubMed - PMC
    1. Pallauf M, Hempel MC, Hupe MC, May M, Haccius M, Weckermann D, Lebentrau S, Hoschke B, Necknig U, Pfitzenmaier J, Manka L, Nuhn P, Törzsök P, Lusuardi L, Merseburger AS (2020) Adherence to the EAU guideline recommendations for local tumor treatment in penile cancer: results of the European PROspective Penile Cancer Study Group Survey (E-PROPS). Adv Ther 37(12):4969–4980. https://doi.org/10.1007/s12325-020-01514-8 - DOI - PubMed - PMC

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