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Editorial
. 2024 Feb 15;209(4):351-352.
doi: 10.1164/rccm.202312-2265ED.

Host Response to Infection: Not All Lymphopenia Is Created Equal in SARS-CoV-2

V Eric Kerchberger  1
Affiliations
Editorial

Host Response to Infection: Not All Lymphopenia Is Created Equal in SARS-CoV-2

V Eric Kerchberger. Am J Respir Crit Care Med. .
No abstract available

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Comment on

  • Host Response Changes and Their Association with Mortality in COVID-19 Patients with Lymphopenia.
    Michels EHA, Appelman B, de Brabander J, van Amstel RBE, van Linge CCA, Chouchane O, Reijnders TDY, Schuurman AR, Sulzer TAL, Klarenbeek AM, Douma RA, Bos LDJ, Wiersinga WJ, Peters-Sengers H, van der Poll T; Amsterdam UMC COVID-19 Biobank Study Group. Michels EHA, et al. Am J Respir Crit Care Med. 2024 Feb 15;209(4):402-416. doi: 10.1164/rccm.202305-0890OC. Am J Respir Crit Care Med. 2024. PMID: 37948687 Free PMC article.

References

    1. Wong LR, Perlman S. Immune dysregulation and immunopathology induced by SARS-CoV-2 and related coronaviruses — are we our own worst enemy? Nat Rev Immunol . 2022;22:47–56. - PMC - PubMed
    1. Huang I, Pranata R. Lymphopenia in severe coronavirus disease-2019 (COVID-19): systematic review and meta-analysis. J Intensive Care . 2020;8:36. - PMC - PubMed
    1. Michels EHA, Appelman B, de Brabander J, van Amstel RBE, van Linge CCA, Chouchane O, et al. COVID-19 Biobank Study Group Host response changes and their association with mortality in COVID-19 patients with lymphopenia. Am J Respir Crit Care Med . 2024;209:402–416. - PMC - PubMed
    1. Calfee CS, Delucchi K, Parsons PE, Thompson BT, Ware LB, Matthay MA, NHLBI ARDS Network Subphenotypes in acute respiratory distress syndrome: latent class analysis of data from two randomised controlled trials. Lancet Respir Med . 2014;2:611–620. - PMC - PubMed
    1. Seymour CW, Kennedy JN, Wang S, Chang CH, Elliott CF, Xu Z, et al. Derivation, validation, and potential treatment implications of novel clinical phenotypes for sepsis. JAMA . 2019;321:2003–2017. - PMC - PubMed