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Comment
. 2024 Mar 15;209(6):763-764.
doi: 10.1164/rccm.202310-1799LE.

Combination of Aroxybutynin and Atomoxetine in Obstructive Sleep Apnea: Is the Effect of One Plus One Greater than Two?

Yanjuan Wu  1 , Qiming Gan  1 , Quanzhen Liu  1   2 , Kang Wu  1
Affiliations
Comment

Combination of Aroxybutynin and Atomoxetine in Obstructive Sleep Apnea: Is the Effect of One Plus One Greater than Two?

Yanjuan Wu et al. Am J Respir Crit Care Med. .
No abstract available

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References

    1. Lee YC, Lu CT, Chuang LP, Lee LA, Fang TJ, Cheng WN, et al. Pharmacotherapy for obstructive sleep apnea - a systematic review and meta-analysis of randomized controlled trials. Sleep Med Rev . 2023;70:101809. - PubMed
    1. Taranto-Montemurro L, Messineo L, Sands SA, Azarbarzin A, Marques M, Edwards BA, et al. The combination of atomoxetine and oxybutynin greatly reduces obstructive sleep apnea severity. A randomized, placebo-controlled, double-blind crossover trial. Am J Respir Crit Care Med . 2019;199:1267–1276. - PMC - PubMed
    1. Schweitzer PK, Taranto-Montemurro L, Ojile JM, Thein SG, Drake CL, Rosenberg R, et al. The combination of aroxybutynin and atomoxetine in the treatment of obstructive sleep apnea (MARIPOSA): a randomized controlled trial. Am J Respir Crit Care Med . 2023;208:1316–1327. - PMC - PubMed
    1. Messineo L, Taranto-Montemurro L, Calianese N, Gell LK, Azarbarzin A, Labarca G, et al. Atomoxetine and fesoterodine combination improves obstructive sleep apnoea severity in patients with milder upper airway collapsibility. Respirology. 2022;27:975–982. - PMC - PubMed
    1. Gottlieb DJ, Punjabi NM. Diagnosis and management of obstructive sleep apnea: a review. JAMA . 2020;323:1389–1400. - PubMed

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