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Comment
. 2024 Mar 15;209(6):764-765.
doi: 10.1164/rccm.202311-2055LE.

Reply to: Combination of Aroxybutynin and Atomoxetine in Obstructive Sleep Apnea: Is the Effect One Plus One Greater Than Two?

Paula K Schweitzer  1
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Comment

Reply to: Combination of Aroxybutynin and Atomoxetine in Obstructive Sleep Apnea: Is the Effect One Plus One Greater Than Two?

Paula K Schweitzer. Am J Respir Crit Care Med. .
No abstract available

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References

    1. Schweitzer PK, Taranto-Montemurro L, Ojile JM, Thein SG, Drake CL, Rosenberg R, et al. The combination of aroxybutynin and atomoxetine in the treatment of obstructive sleep apnea (MARIPOSA): a randomized controlled trial. Am J Respir Crit Care Med . 2023;208:1316–1327. - PMC - PubMed
    1. Taranto-Montemurro L, Messineo L, Sands SA, Azarbarzin A, Marques M, Edwards BA, et al. The combination of atomoxetine and oxybutynin greatly reduces obstructive sleep apnea severity. A randomized, placebo-controlled, double-blind crossover trial. Am J Respir Crit Care Med . 2019;199:1267–1276. - PMC - PubMed
    1. Sangal RB, Sangal JM, Thorp K. Atomoxetine improves sleepiness and global severity of illness but not the respiratory disturbance index in mild to moderate obstructive sleep apnea with sleepiness. Sleep Med . 2008;9:506–510. - PubMed
    1. Schweitzer PK, Maynard JP, Wylie PE, Emsellem HA, Sands SA. Efficacy of atomoxetine plus oxybutynin in the treatment of obstructive sleep apnea with moderate pharyngeal collapsibility. Sleep Breath . 2023;27:495–503. - PMC - PubMed
    1. Taranto-Montemurro L, Messineo L, Azarbarzin A, Vena D, Hess LB, Calianese NA, et al. Effects of the combination of atomoxetine and oxybutynin on OSA endotypic traits. Chest. 2020;157:1626–1636. - PMC - PubMed

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