Efficacy and safety of single microneedle radiofrequency vs . photodynamic therapy on moderate-to-severe acne vulgaris: A prospective, randomized, controlled study

Chuchu Huang^{1

2

3}, Mengping Mao^{1

2}, Yiran Peng^{1

2

3}, Ben Wang^{1

2

3}, Yuxuan Deng⁴, Hongfu Xie^{1

2

3}, Dan Jian^{1

2

3}

Affiliations

¹ Department of Dermatology, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China.
² National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China.
³ Hunan Key Laboratory of Aging Biology, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China.
⁴ Department of Dermatology and Allergy, and Christine Kühne-Center for Allergy Research and Education, University Hospital of Bonn, D-53127, Bonn, Germany.

PMID: 38192026
PMCID: PMC11046016
DOI: 10.1097/CM9.0000000000002911

Randomized Controlled Trial

Efficacy and safety of single microneedle radiofrequency vs . photodynamic therapy on moderate-to-severe acne vulgaris: A prospective, randomized, controlled study

Chuchu Huang et al. Chin Med J (Engl). 2024.

. 2024 Apr 20;137(8):1006-1008.

doi: 10.1097/CM9.0000000000002911. Epub 2024 Jan 9.

Authors

Chuchu Huang^{1

2

3}, Mengping Mao^{1

2}, Yiran Peng^{1

2

3}, Ben Wang^{1

2

3}, Yuxuan Deng⁴, Hongfu Xie^{1

2

3}, Dan Jian^{1

2

3}

Affiliations

¹ Department of Dermatology, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China.
² National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China.
³ Hunan Key Laboratory of Aging Biology, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China.
⁴ Department of Dermatology and Allergy, and Christine Kühne-Center for Allergy Research and Education, University Hospital of Bonn, D-53127, Bonn, Germany.

PMID: 38192026
PMCID: PMC11046016
DOI: 10.1097/CM9.0000000000002911

No abstract available

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Conflict of interest statement

None.

Figures

**Figure 1**
Clinical improvements were observed in both groups. Photographs of the MRF group (A) and the PDT group (B) at BL, PT1, 2, 3 and the final F/U. BL: Baseline; F/U: Follow-up; MRF: Single Microneedle Radiofrequency therapy; PDT: Photodynamic therapy; PT: Post-treatment.

See this image and copyright information in PMC

References

1. Zhang JZ, Xiang F, Yu SR, Luo D, Li TT, Kang XJ. Association between acne and smoking: Systematic review and meta-analysis of observational studies. Chin Med J 2021;134:1887–1888. doi: 10.1097/CM9.0000000000001286. - PMC - PubMed
1. Chilicka K, Rusztowicz M, Szyguła R, Nowicka D. Methods for the improvement of acne scars used in dermatology and cosmetology: A review. J Clin Med 2022;11:2744. doi: 10.3390/jcm11102744. - PMC - PubMed
1. Ahn GR, Kim JM, Park SJ, Li K, Kim BJ. Selective sebaceous gland electrothermolysis using a single microneedle radiofrequency device for acne patients: A prospective randomized controlled study. Lasers Surg Med 2020;52:396–401. doi: 10.1002/lsm.23152. - PubMed
1. Wiegell SR, Wulf HC. Photodynamic therapy of acne vulgaris using 5-aminolevulinic acid versus methyl aminolevulinate. J Am Acad Dermatol 2006;54:647–651. doi: 10.1016/j.jaad.2005.12.033. - PubMed
1. Al Qarqaz F, Al-Yousef A. Skin microneedling for acne scars associated with pigmentation in patients with dark skin. J Cosmet Dermatol 2018;17:390–395. doi: 10.1111/jocd.12520. - PubMed

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Efficacy and safety of single microneedle radiofrequency vs . photodynamic therapy on moderate-to-severe acne vulgaris: A prospective, randomized, controlled study

Affiliations

Efficacy and safety of single microneedle radiofrequency vs . photodynamic therapy on moderate-to-severe acne vulgaris: A prospective, randomized, controlled study

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