Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2023 Dec;11(4):187-194.
doi: 10.1016/j.prnil.2023.04.002. Epub 2023 Apr 18.

Single-port and multiport robot-assisted radical prostatectomy: A meta-analysis

Tuan Thanh Nguyen  1   2   3 , Ryan W Dobbs  4 , Huy Gia Vuong  5 , Khoa Quy  2 , Hanh Thi Tuyet Ngo  2 , Anh Tuan Mai  2 , Mai Tran Thi Tuyet  2 , Minh Sam Thai  2   3 , Ho Yee Tiong  6 , Se Young Choi  7 , Mohammed Shahait  8 , David I Lee  1
Affiliations
Review

Single-port and multiport robot-assisted radical prostatectomy: A meta-analysis

Tuan Thanh Nguyen et al. Prostate Int. 2023 Dec.

Abstract

Objective: To compare the perioperative, oncological, and functional outcomes between single-port robot-assisted radical prostatectomy (SP-RARP) and multiport robot-assisted radical prostatectomy (MP-RARP) via a meta-analysis.

Methods: For relevant articles, three electronic databases, including PubMed, Scopus, and Web of Science, were searched from their inception until January 15, 2022. A meta-analysis has been reported in line with PRISMA 2020 and AMSTAR Guidelines. The risk ratio and weighted mean difference (MD) were applied for the comparison of dichotomous and continuous variables with 95% confidence intervals (CI).

Results: Of the 368 retrieved abstracts, 41 underwent full-text review, and seven studies were included in the final analysis, comprising a total cohort of 1,934 cases of RARP (355 SP-RARP cases and 1,579 MP-RARP cases). Compared to MP-RARP, the SP-RARP group had less postoperative pain score (MD = -0.7, 95% CI -1 to -0.4, P<0.001), morphine milligram equivalents usage (MD = -3.8, 95% CI -7.5 to -0.1, P=0.04), hospital stay (MD = -1, 95% CI -1.8 to -0.1, P=0.019), and urinary catheterization time (MD = -1.1, 95% CI -1.9 to -0.3, P=0.008). However, the SP-RARP group had a longer console time than the MP-RARP group (MD = 5.3, 95% CI 2.6 to 7.9, P<0.001).

Conclusions: Our study demonstrated that early results were mostly equivalent with the single-port approach. This technology may help to reduce the hospital stay and postoperative pain for patients undergoing radical prostatectomy compared to MP-RARP, without compromising the functional and early oncological outcomes.

Keywords: Functional outcomes; Meta-analysis; Oncologic outcomes; Prostate cancer; Radical prostatectomy; Robotic surgery; Single-port.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Evidence acquisition flow chart. ∗Records excluded due to single-arm study design or lack of information related with perioperative, functional, and oncological outcomes; ∗∗Includes no reliable or overlapped data.
Figure 2
Figure 2
Forest plots for the meta-analysis comparing the outcomes between single-port and multiport robot-assisted radical prostatectomy: (A) operative time; (B) console time; (C) estimated blood loss; (D) postoperative pain score; (E) morphine milligram equivalents.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Collaboration GBoDC. Global, regional, and national cancer incidence, mortality, years of life lost, years lived with disability, and disability-adjusted life-years for 32 cancer groups, 1990 to 2015: a systematic analysis for the global burden of disease study. JAMA Oncol. 2017;3(4):524–548. - PMC - PubMed
    1. Siegel R.L., Miller K.D., Fuchs H.E., Jemal A. Cancer statistics, 2022. CA A Cancer J Clin. 2022;72(1):7–33. - PubMed
    1. Papachristodoulou A., Abate-Shen C. Precision intervention for prostate cancer: re-evaluating who is at risk. Cancer Lett. 2022;538 - PMC - PubMed
    1. Renzulli J.F., Brito J., Kim I.Y., Broccoli I. A meta-analysis on the use of radiotherapy after prostatectomy: adjuvant versus early salvage radiation. Prostate International. 2022;10(2):80–84. - PMC - PubMed
    1. Wallis C.J.D., Saskin R., Choo R., Herschorn S., Kodama R.T., Satkunasivam R., et al. Surgery versus radiotherapy for clinically-localized prostate cancer: a systematic review and meta-analysis. Eur Urol. 2016;70(1):21–30. - PubMed