Kidney macrophages tap the stream
- PMID: 38198853
- DOI: 10.1016/j.immuni.2023.12.008
Kidney macrophages tap the stream
Abstract
Tissue-resident macrophages are essential for maintaining organismal homeostasis, but the precise mechanisms that macrophages use to perform this function are not fully understood. In this issue of Immunity, He et al. demonstrate that renal macrophages surveil and sample urine particles, ensuring optimal collecting duct flow and preventing kidney stone development.
Copyright © 2023 Elsevier Inc. All rights reserved.
Conflict of interest statement
Declaration of interests J.S.A.P. is the co-founder of Atish Technologies.
Comment on
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Renal macrophages monitor and remove particles from urine to prevent tubule obstruction.Immunity. 2024 Jan 9;57(1):106-123.e7. doi: 10.1016/j.immuni.2023.12.003. Epub 2023 Dec 29. Immunity. 2024. PMID: 38159573
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