Clinical outcomes and management of JAK inhibitor-associated acne in patients with moderate-to-severe atopic dermatitis undergoing upadacitinib: A multicenter retrospective study

Gianluca Avallone¹, Luca Mastorino², Gianluca Tavoletti³, Nicole Macagno², Francesca Barei³, Donatella Schena⁴, Mariateresa Rossi⁵, Elisabetta Magnaterra⁶, Flaminia Antonelli⁷, Graziella Babino⁸, Riccardo Viola⁹, Luigi Gargiulo¹⁰, Claudio Conforti¹¹, Luca Rapparini¹², Enzo Errichetti¹³, Cataldo Patruno¹⁴, Pasqualina Ruggiero¹⁵, Gabriele Roccuzzo², Carlo A Maronese³, Giampiero Girolomoni⁴, Massimo Gola⁶, Andrea Chiricozzi⁷, Anna Balato⁸, Francesca Ambrogio⁹, Alessandra Narcisi¹⁰, Iris Zalaudek¹⁶, Carlotta Gurioli¹², Maddalena Napolitano¹⁵, Angelo V Marzano³, Caterina Foti⁹, Antonio Costanzo¹⁰, Bianca M Piraccini¹², Silvia M Ferrucci³, Michela Ortoncelli², Pietro Quaglino², Simone Ribero²

Affiliations

¹ Department of Medical Sciences, University of Turin, Dermatology Clinic, Turin, Italy; Dermatology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy; Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy. Electronic address: gianluca.avallone2@gmail.com.
² Department of Medical Sciences, University of Turin, Dermatology Clinic, Turin, Italy.
³ Dermatology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy; Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.
⁴ Section of Dermatology and Venereology, Department of Medicine, University of Verona, Verona, Italy.
⁵ Dermatology Department, University of Brescia, Brescia, Italy.
⁶ Section of Dermatology, Department of Health Sciences, University of Florence, Florence, Italy.
⁷ UOC di Dermatologia, Dipartimento di Scienze Mediche e Chirurgiche, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Rome, Italy; Dermatologia, Dipartimento di Medicina e Chirurgia Traslazionale, Università Cattolica del Sacro Cuore, Rome, Italy.
⁸ Unit of Dermatology, University of Campania Luigi Vanvitelli, Naples, Italy.
⁹ Department of Precision and Regenerative Medicine and Ionian Area, Unit of Dermatology, University of Bari Aldo Moro, Bari, Italy.
¹⁰ Dermatology Unit, IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milano, Italy.
¹¹ Dermatology Clinic, Maggiore Hospital of Trieste, Trieste, Italy; IDI-IRCCS, Dermatological Research Hospital, Rome, Italy.
¹² Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Department of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna, Bologna, Italy.
¹³ Institute of Dermatology, Azienda Sanitaria Universitaria Friuli Centrale (ASU FC), University of Udine, Udine, Italy.
¹⁴ Department of Health Sciences, University Magna Graecia of Catanzaro, Catanzaro, Italy.
¹⁵ Section of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy.
¹⁶ Dermatology Clinic, Maggiore Hospital of Trieste, Trieste, Italy.

PMID: 38199282
DOI: 10.1016/j.jaad.2024.01.004

Multicenter Study

Clinical outcomes and management of JAK inhibitor-associated acne in patients with moderate-to-severe atopic dermatitis undergoing upadacitinib: A multicenter retrospective study

Gianluca Avallone et al. J Am Acad Dermatol. 2024 May.

. 2024 May;90(5):1031-1034.

doi: 10.1016/j.jaad.2024.01.004. Epub 2024 Jan 9.

Authors

Affiliations

¹ Department of Medical Sciences, University of Turin, Dermatology Clinic, Turin, Italy; Dermatology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy; Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy. Electronic address: gianluca.avallone2@gmail.com.
² Department of Medical Sciences, University of Turin, Dermatology Clinic, Turin, Italy.
³ Dermatology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy; Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.
⁴ Section of Dermatology and Venereology, Department of Medicine, University of Verona, Verona, Italy.
⁵ Dermatology Department, University of Brescia, Brescia, Italy.
⁶ Section of Dermatology, Department of Health Sciences, University of Florence, Florence, Italy.
⁷ UOC di Dermatologia, Dipartimento di Scienze Mediche e Chirurgiche, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Rome, Italy; Dermatologia, Dipartimento di Medicina e Chirurgia Traslazionale, Università Cattolica del Sacro Cuore, Rome, Italy.
⁸ Unit of Dermatology, University of Campania Luigi Vanvitelli, Naples, Italy.
⁹ Department of Precision and Regenerative Medicine and Ionian Area, Unit of Dermatology, University of Bari Aldo Moro, Bari, Italy.
¹⁰ Dermatology Unit, IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milano, Italy.
¹¹ Dermatology Clinic, Maggiore Hospital of Trieste, Trieste, Italy; IDI-IRCCS, Dermatological Research Hospital, Rome, Italy.
¹² Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Department of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna, Bologna, Italy.
¹³ Institute of Dermatology, Azienda Sanitaria Universitaria Friuli Centrale (ASU FC), University of Udine, Udine, Italy.
¹⁴ Department of Health Sciences, University Magna Graecia of Catanzaro, Catanzaro, Italy.
¹⁵ Section of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy.
¹⁶ Dermatology Clinic, Maggiore Hospital of Trieste, Trieste, Italy.

PMID: 38199282
DOI: 10.1016/j.jaad.2024.01.004

No abstract available

Keywords: JAK inhibitors; acne; acneiform eruption; atopic dermatitis; side effects; upadacitinib.

PubMed Disclaimer

Conflict of interest statement

Conflicts of interest None disclosed.

Publication types

Actions

MeSH terms

Actions
Actions
Actions
Actions
Actions
Actions
Actions

Substances

Actions
Actions
Actions

LinkOut - more resources

Full Text Sources
Medical
- MedlinePlus Health Information

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

Clinical outcomes and management of JAK inhibitor-associated acne in patients with moderate-to-severe atopic dermatitis undergoing upadacitinib: A multicenter retrospective study

Affiliations

Clinical outcomes and management of JAK inhibitor-associated acne in patients with moderate-to-severe atopic dermatitis undergoing upadacitinib: A multicenter retrospective study

Authors

Affiliations

Conflict of interest statement

Publication types

MeSH terms

Substances

LinkOut - more resources

Full Text Sources

Medical