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Comment
. 2024 Feb;23(2):104.
doi: 10.1038/d41573-024-00003-9.

Modified mRNA produces frameshifted peptides

Sarah Crunkhorn
Comment

Modified mRNA produces frameshifted peptides

Sarah Crunkhorn. Nat Rev Drug Discov. 2024 Feb.
No abstract available

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Comment on

  • N1-methylpseudouridylation of mRNA causes +1 ribosomal frameshifting.
    Mulroney TE, Pöyry T, Yam-Puc JC, Rust M, Harvey RF, Kalmar L, Horner E, Booth L, Ferreira AP, Stoneley M, Sawarkar R, Mentzer AJ, Lilley KS, Smales CM, von der Haar T, Turtle L, Dunachie S, Klenerman P, Thaventhiran JED, Willis AE. Mulroney TE, et al. Nature. 2024 Jan;625(7993):189-194. doi: 10.1038/s41586-023-06800-3. Epub 2023 Dec 6. Nature. 2024. PMID: 38057663 Free PMC article.

References

    1. Mulroney, T. E. et al. N1-methylpseudouridylation of mRNA causes +1 ribosomal frameshifting. Nature 625, 189–194 (2024) - PubMed - DOI

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