Targeting glial lipid metabolism to tackle neurodegeneration

Comment

Katie Kingwell. Nat Rev Drug Discov. 2024 Feb.

. 2024 Feb;23(2):106.

doi: 10.1038/d41573-024-00004-8.

No abstract available

Comment on

Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist.
Litvinchuk A, Suh JH, Guo JL, Lin K, Davis SS, Bien-Ly N, Tycksen E, Tabor GT, Remolina Serrano J, Manis M, Bao X, Lee C, Bosch M, Perez EJ, Yuede CM, Cashikar AG, Ulrich JD, Di Paolo G, Holtzman DM. Litvinchuk A, et al. Neuron. 2024 Feb 7;112(3):384-403.e8. doi: 10.1016/j.neuron.2023.10.023. Epub 2023 Nov 22. Neuron. 2024. PMID: 37995685 Free PMC article.

1. Litvinchuk, A. et al. Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist. Neuron https://doi.org/10.1016/j.neuron.2023.10.023 (2023).