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Review
. 2023 Dec 21;13(1):55.
doi: 10.3390/jcm13010055.

Tailoring Rheumatoid Arthritis Treatment through a Sex and Gender Lens

Loreto Carmona  1 , Elena Aurrecoechea  2 , María Jesús García de Yébenes  1
Affiliations
Review

Tailoring Rheumatoid Arthritis Treatment through a Sex and Gender Lens

Loreto Carmona et al. J Clin Med. .

Abstract

Rheumatoid arthritis (RA) occurs more frequently in women than in men, and the studies that have addressed clinical and prognostic differences between the sexes are scarce and have contradictory results and methodological problems. The present work aims to evaluate sex- and gender-related differences in the clinical expression and prognosis of RA as well as on the impact on psychosocial variables, coping behavior, and healthcare use and access. By identifying between sex differences and gender-related outcomes in RA, it may be possible to design tailored therapeutic strategies that consider the differences and unmet needs. Being that sex, together with age, is the most relevant biomarker and health determinant, a so-called personalized medicine approach to RA must include clear guidance on what to do in case of differences.

Keywords: gender; personalized medicine; rheumatoid arthritis; sex.

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Conflict of interest statement

The authors declare no conflict of interest.

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