doi: 10.1099/00222615-23-1-1.
Opsonic monoclonal antibodies against lipopolysaccharide antigens of Leptospira interrogans serovar hardjo
- PMID: 3820267
- DOI: 10.1099/00222615-23-1-1
Item in Clipboard
Opsonic monoclonal antibodies against lipopolysaccharide antigens of Leptospira interrogans serovar hardjo
J Med Microbiol.
1987 Feb.
Abstract
Six monoclonal antibodies produced from mice immunised with Leptospira interrogans serovar hardjo were directed against determinants in the leptospiral lipopolysaccharide, as indicated by immunodiffusion and enzyme immunoassay (EIA), and opsonised leptospires for phagocytosis by mouse macrophages. Their specificities were studied by agglutination and EIA. Five antibodies reacted with some, but not all, members of the Sejroe and Hebdomadis serogroups, and one antibody agglutinated exclusively members of the Sejroe group thus indentifying a serogroup-specific epitope. None of the six antibodies reacted with representative serovars of any other serogroup.
Similar articles
-
A monoclonal antibody reacting with a determinant on leptospiral lipopolysaccharide protects guinea pigs against leptospirosis.J Med Microbiol. 1986 Nov;22(3):269-75. doi: 10.1099/00222615-22-3-269. J Med Microbiol. 1986. PMID: 2430103
-
Monoclonal antibodies reacting with serogroup and serovar specific epitopes on different lipopolysaccharide subunits of Leptospira interrogans serovar pomona.FEMS Microbiol Immunol. 1989 Mar;1(4):213-8. doi: 10.1111/j.1574-6968.1989.tb02385.x. FEMS Microbiol Immunol. 1989. PMID: 2483523
-
Immunochemical studies of opsonic epitopes of the lipopolysaccharide of Leptospira interrogans serovar hardjo.FEMS Immunol Med Microbiol. 1994 Feb;8(2):99-107. doi: 10.1111/j.1574-695X.1994.tb00431.x. FEMS Immunol Med Microbiol. 1994. PMID: 7513591
-
Serogroup and serotype classification of bacterial pathogens.Methods Enzymol. 1994;235:159-74. doi: 10.1016/0076-6879(94)35138-4. Methods Enzymol. 1994. PMID: 8057893 Review. No abstract available.
-
Monoclonal antibodies against rat macrophages.J Immunol Methods. 1994 Sep 14;174(1-2):21-3. doi: 10.1016/0022-1759(94)90006-x. J Immunol Methods. 1994. PMID: 8083524 Review. No abstract available.
Cited by
-
Identification of potential Leptospira phosphoheptose isomerase inhibitors through virtual high-throughput screening.Genomics Proteomics Bioinformatics. 2010 Dec;8(4):246-55. doi: 10.1016/S1672-0229(10)60026-5. Genomics Proteomics Bioinformatics. 2010. PMID: 21382593 Free PMC article.
-
Production and characterization of monoclonal antibodies specific for Leptospira borgpetersenii serovar hardjo type hardjobovis and Leptospira interrogans serovar hardjo type hardjoprajitno.Can J Vet Res. 1999 Jan;63(1):62-8. Can J Vet Res. 1999. PMID: 9918336 Free PMC article.
-
Production and characterization of monoclonal antibodies against Serpulina hyodysenteriae and S. innocens and their use in serotyping.J Clin Microbiol. 1995 Sep;33(9):2519-21. doi: 10.1128/jcm.33.9.2519-2521.1995. J Clin Microbiol. 1995. PMID: 7494066 Free PMC article.
-
Global analysis of outer membrane proteins from Leptospira interrogans serovar Lai.Infect Immun. 2002 May;70(5):2311-8. doi: 10.1128/IAI.70.5.2311-2318.2002. Infect Immun. 2002. PMID: 11953365 Free PMC article.
-
Identification and characterization of the dTDP-rhamnose biosynthesis and transfer genes of the lipopolysaccharide-related rfb locus in Leptospira interrogans serovar Copenhageni.J Bacteriol. 1997 Feb;179(4):1262-7. doi: 10.1128/jb.179.4.1262-1267.1997. J Bacteriol. 1997. PMID: 9023210 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
