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. 2023 Aug 1;5(6):836-838.
doi: 10.1016/j.jaccao.2023.05.012. eCollection 2023 Dec.

Prospective Screening for Transthyretin Cardiac Amyloidosis in Spinal Stenosis Surgery Patients: Results of the CASS Study

Philippe Debonnaire, Mathias Claeys, Pascale De Paepe, Emma Christiaen, Bert Geerts, Frank De Geeter, Sander Trenson, Davy Hoste, Jan Van Droogenbroeck, Kristof Verhoeven, Nikolaas Vantomme, René Tavernier

Prospective Screening for Transthyretin Cardiac Amyloidosis in Spinal Stenosis Surgery Patients: Results of the CASS Study

Philippe Debonnaire et al. JACC CardioOncol. .
No abstract available

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Figures

Figure 1
Figure 1
Presence, Burden, and Relevance of ATTR Amyloid Deposition in Ligamentum Flavum Biopsy (A) Transthyretin amyloid presence and burden according to age category. Age was an independent predictor of ATTR amyloid presence; however, high burden (Westermark grade 4) was similarly distributed among age categories, starting from age onset of >60 years old. (B) Relevance of high ATTR amyloid burden. Concomitant ATTR cardiomyopathy was found only in patients with Westermark grade 4 deposition, present in 21% of subjects with ATTR amyloid-positive ligamentum flavum biopsy.
See this image and copyright information in PMC

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