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Case Reports
. 2023 Nov 10;2(4):343-348.
doi: 10.1016/j.imj.2023.11.002. eCollection 2023 Dec.

Persistent Nocardia beijingensis infection in a patient with postoperative abscess and misuse of antibiotics in China

Lihua Qi  1 , Weihong Fan  1 , Jing Li  2 , Hongfei Cui  3 , Jianxia Xu  1 , Dongmei Gu  1 , Jiaojiao Meng  4 , Jie Liu  1   5
Affiliations
Case Reports

Persistent Nocardia beijingensis infection in a patient with postoperative abscess and misuse of antibiotics in China

Lihua Qi et al. Infect Med (Beijing). .

Abstract

Here we describe the first case of abscess infection caused by Nocardia beijingensis in China. The patient was immunocompetent but suffered from postoperative abscess for 6 years. This study highlights the necessity of long-term infected foci to be thoroughly examined to identify the pathogen, as well as the importance of accurate Nocardia identification and antimicrobial susceptibility tests for understanding the pathogen's epidemiology, clinical significance, and treatment strategy.

Keywords: Abscess; Immunocompetent; Infection; Nocardia beijingensis.

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Graphical abstract
Fig 1
Fig. 1
(A) Computed tomography of the patient's chest, revealing a dense shadow in the lower margin of the sternum. (B) Histological features of the infected foci, showing fibrous tissue with nonspecific inflammatory changes indicated with green and yellow arrows. (C) Gram's staining. (D) Ziehl-Neelsen staining.
Fig 2
Fig. 2
Phylogenetic relationships of the isolate (Nocardia beijingensis strain 942817 China, highlighted in red) compared with reference strains. Trimmed 16S rRNA were aligned using MEGA 7.26 software. The strain ID, country source, and GenBank accession number are indicated. The scale bar indicates the nucleotide substitutions per site.
See this image and copyright information in PMC

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