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. 2023 Nov 17;2(4):315-323.
doi: 10.1016/j.imj.2023.11.005. eCollection 2023 Dec.

Chikungunya in Zhejiang Province, Southeast China

Jiangping Ren  1   2   3 , Feng Ling  1   2   3 , Ying Liu  1 , Jimin Sun  1   2   3
Affiliations

Chikungunya in Zhejiang Province, Southeast China

Jiangping Ren et al. Infect Med (Beijing). .

Abstract

Background: Chikungunya is emerging and reemerging word-widely in the past decades. It is non-endemic in Zhejiang Province, Southeast China. Aedes albopictus, one of major vectors of chikungunya, is widely-distribution in Zhejiang, and autochthonous transmission is possible after introducing chikungunya virus.

Methods: Retrospectively collected the epidemiological, clinical and genetic data of chikungunya and conducted the descriptive analysis and gene sequence analysis.

Results: From 2008 to 2022, 29 chikungunya cases, including 26 overseas imported and 3 local cases, were reported and no cases died of chikungunya. More than half of the imported cases (53.85%) were from Southeast Asia. Seasonal peak of the imported cases was noted between August and September, and 42.31% cases onset in those 2 months. Eight prefecture-level cities and 16 counties reported cases during the study period, with Jinghua (27.59%) and Hangzhou (24.14%) reporting the largest number of cases. The 3 local cases were all reported in Qujiang, Quzhou in 2017. For imported cases, the male-female gender ratio was 2.71:1, 20-30 years old cases (46.15%) and commercial service (42.31%) accounted for the highest proportion. Clinically, fever (100%), fatigue (94.44%), arthralgia (79.17%), headache (71.43%) and erythra (65.22%) were the most common reported symptoms. Eight whole-genome sequences were obtained and belonged to East/Central/South African (ECSA) or Asian genotype.

Conclusions: With the change of immigration policy, the surveillance of chikungunya should be strengthened and the ability of the case discovery and diagnosis should be improved in Zhejiang in the post-COVID-19 era.

Keywords: Chikungunya; Epidemiological characteristics; Imported cases.

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Image, graphical abstract
Graphical abstract
Fig1
Fig. 1
The temporal distribution of chikungunya fever in Zhejiang province during 2008–2022.
Fig2
Fig. 2
The geographical distribution of chikungunya fever in Zhejiang province during 2008–2022. (http://www.geodata.cn/data/datadetails.html?dataguid=258898130861140&docid=6835).
Fig3
Fig. 3
The age distribution of chikungunya fever in Zhejiang province during 2008–2022.
Fig 4
Fig. 4
The clinical spectrum of chikungunya cases in Zhejiang province from 2008 to 2022.
Fig5
Fig. 5
Phylogenetic tree of chikungunya strains based on complete genome sequence.
See this image and copyright information in PMC

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