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. 2024 May;79(5):535-541.
doi: 10.1111/anae.16206. Epub 2024 Jan 11.

Emergency treatment of peri-operative anaphylaxis: Resuscitation Council UK algorithm for anaesthetists

A Dodd  1 , P J Turner  2 , J Soar  3 , L Savic  4 ; representing the UK Perioperative Allergy Network
Affiliations
Free article

Emergency treatment of peri-operative anaphylaxis: Resuscitation Council UK algorithm for anaesthetists

A Dodd et al. Anaesthesia. 2024 May.
Free article

Abstract

Peri-operative anaphylaxis is a rare but potentially catastrophic event which must be considered whenever unexpected and significant cardiovascular or respiratory compromise occurs during anaesthesia. The Resuscitation Council UK algorithm for peri-operative anaphylaxis highlights the importance of early intravenous adrenaline and fluid resuscitation and provides guidance on the treatment of refractory anaphylaxis and immediate follow-up. This algorithm is endorsed by the Royal College of Anaesthetists, Association of Anaesthetists, British Society of Allergy and Clinical Immunology and Clinical Immunology Professional Network of the British Society for Immunology. This document was produced by the Perioperative Allergy Network steering committee in collaboration with the Resuscitation Council UK.

Keywords: Resucscitation Council UK; intravenous adrenaline; peri-operative anaphylaxis; perioperative Allergy Network.

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References

    1. Resuscitation Council UK. Emergency treatment of anaphylaxis: guidelines for healthcare providers. 2021. https://www.resus.org.uk/library/additional‐guidance/guidance‐anaphylaxi... (accessed 24/08/2023).
    1. Garvey LH, Dewachter P, Hepner DL, et al. Management of suspected immediate perioperative allergy reactions: an international overview and consensus recommendations. British Journal of Anaesthesia 2019; 123: e50–e64.
    1. Garvey LH, Ebo DG, Mertes PM, et al. An EAACI position paper on the investigation of perioperative immediate hypersensitivity reactions. Allergy 2019; 74: 1872–1884.
    1. Association of Anaesthetists. Quick Reference Handbook. Anaphylaxis. 2022. www.anaesthetists.org/qrh (accessed 24/08/2023).
    1. Mertes PM, Ebo DG, Garcez T, et al. Comparative epidemiology of suspected perioperative hypersensitivity reactions. British Journal of Anaesthesia 2019; 123: e16–e28.

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