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. 2023 Dec 29;102(52):e36794.
doi: 10.1097/MD.0000000000036794.

Children autism spectrum disorder and gut microbiota: A bibliometric and visual analysis from 2000 to 2023

Xing-Ruo Gong  1 , Xiao-Rui You  1 , Mei-Ran Guo  1 , Xue-Ying Ding  2 , Bing-Xiang Ma  3
Affiliations

Children autism spectrum disorder and gut microbiota: A bibliometric and visual analysis from 2000 to 2023

Xing-Ruo Gong et al. Medicine (Baltimore). .

Abstract

Autism spectrum disorder (ASD) has evolved from a narrow and rare childhood-onset disorder to a widely publicized and researched lifelong disease recognized as common and significantly heterogeneous. Researchers have suggested that gastrointestinal symptoms in ASD may be a manifestation of an underlying inflammatory process. However, there is a lack of bibliometric analysis of ASD and gut microbiota in children. Accordingly, this study conducts a bibliometric analysis of ASD and gut microbiota in children from 2000 to 2023, explores the current status and cutting-edge trends in the field of ASD and gut microbiota in children, and identifies new directions for future research. The literature on ASD and gut microbiota in children was screened using the Web of Science Core Collection from 2000 to 2023. Annual publications, countries, institutions, authors, journals, keywords, and references were visualized and analyzed using CiteSpace 5.8. R3 and VOSviewer1.6.18. This study included 1071 publications. Since the beginning of 2011, the overall number of articles shows an upward trend. The most productive country and institution are the United States and the University of California system, respectively. The most frequently cited author is Kang Dae-Wook, with 790 citations, who has contributed significantly to this field. Timothy Dinan is the most prolific author, with 34 articles. The journal with the most published articles on this topic is Nutrients, whereas PLOS One is the most cited journal. The most used keyword is "gut microbiota," and the reference for the highest outbreak intensity is Hsiao. The research hotspots and trends predicted in this study provide a reference for further in-depth research in this field.

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Conflict of interest statement

The authors have no conflicts of interest to disclose.

Figures

Figure 1.
Figure 1.
Flowchart of literature identification and selection.
Figure 2.
Figure 2.
Trends of publications in the field of autism spectrum disorder and gut microbiota in children (2000–2023).
Figure 3.
Figure 3.
(A) Analysis of countries and institutions: CiteSpace network map of countries involved in studying autism spectrum disorder and gut microbiota in children. (B) Analysis of countries and institutions: VOSviewer network map of countries involved in studying autism spectrum disorder and gut microbiota in children. (C). Analysis of countries and institutions: CiteSpace network map of institutions involved in studying autism spectrum disorder and gut microbiota in children. (D) Analysis of countries and institutions: VOSviewer network map of institutions involved in studying autism spectrum disorder and gut microbiota in children.
Figure 4.
Figure 4.
(A) Analysis of authors: visualization of authors. (B) Analysis of authors: visualization of cited authors.
Figure 5.
Figure 5.
(A) Analysis of journals: visualization of cited journals. (B) Analysis of journals: overlay of graphs representing research in autism spectrum disorder and gut microbiota in children.
Figure 6.
Figure 6.
(A) Cluster analysis and visualization of keywords. (B) Analysis of keywords: top 25 keywords with the strongest citation bursts.
Figure 7.
Figure 7.
Timeline view of keywords.
Figure 8.
Figure 8.
Top 25 most cited references with the strongest citation bursts.
See this image and copyright information in PMC

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