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Multicenter Study
. 2024 Jan 11;19(1):e0296056.
doi: 10.1371/journal.pone.0296056. eCollection 2024.

Clinical features, socioeconomic status, management, short and long-term outcomes of patients with acute myocardial infarction: Phase I results of PEACE MENA registry

Ayman Al Saleh  1 , Amal Jamee  2   3 , Kadhim Sulaiman  4 , Mohamed Sobhy  5 , Habib Gamra  6 , Fahad Alkindi  7 , Salim Benkhedda  8 , Ahmed Al-Motarreb  9 , Mohammad I Amin  10 , Wael Almahmeed  11 , Ayman Hammoudeh  12 , Hadi Skouri  13 , Hasan A Farhan  14 , Mohammad Al Jarallah  15 , Nadia Fellat  16 , Prashanth Panduranga  4 , Bayan K Alnajm  17 , Magdy Abdelhamid  18 , Rafik Refaat  5 , Hassen Amor  19 , Salma Messaous  6 , Hosameldin S Ahmed  7 , Ahcene Chibane  20 , Azzouz AbdulMalek  8 , Nora K Alsagheer  21 , Sobhi Dada  22 , Zaki Mokhtar  23 , Muhammad Ali  24 , Anhar Ullah  1   25 , Hanan AlBackr  1 , Khalid F Alhabib  1
Affiliations
Multicenter Study

Clinical features, socioeconomic status, management, short and long-term outcomes of patients with acute myocardial infarction: Phase I results of PEACE MENA registry

Ayman Al Saleh et al. PLoS One. .

Abstract

Background: The Program for the Evaluation and Management of Cardiac Events in the Middle East and North Africa (PEACE MENA) is a prospective registry program in Arabian countries that involves in patients with acute myocardial infarction (AMI) or acute heart failure (AHF).

Methods: This prospective, multi-center, multi-country study is the first report of the baseline characteristics and outcomes of inpatients with AMI who were enrolled during the first 14-month recruitment phase. We report the clinical characteristics, socioeconomic, educational levels, and management, in-hospital, one month and one-year outcomes.

Results: Between April 2019 and June 2020, 1377 patients with AMI were enrolled (79.1% males) from 16 Arabian countries. The mean age (± SD) was 58 ± 12 years. Almost half of the population had a net income < $500/month, and 40% had limited education. Nearly half of the cohort had a history of diabetes mellitus, hypertension, or hypercholesterolemia; 53% had STEMI, and almost half (49.7%) underwent a primary percutaneous intervention (PCI) (lowest 4.5% and highest 100%). Thrombolytics were used by 36.2%. (Lowest 6.45% and highest (90.9%). No reperfusion occurred in 13.8% of patients (lowest was 0% and highest 72.7%).Primary PCI was performed less frequently in the lower income group vs. high income group (26.3% vs. 54.7%; P<0.001). Recurrent ischemia occurred more frequently in the low-income group (10.9% vs. 7%; P = 0.018). Re-admission occurred in 9% at 1 month and 30% at 1 year, whereas 1-month mortality was 0.7% and 1-year mortality 4.7%.

Conclusion: In the MENA region, patients with AMI present at a young age and have a high burden of cardiac risk factors. Most of the patients in the registry have a low income and low educational status. There is heterogeneity among key performance indicators of AMI management among various Arabian countries.

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Conflict of interest statement

The authors have declared that no competing interests exist.

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