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. 2023 Dec 12;15(12):e50375.
doi: 10.7759/cureus.50375. eCollection 2023 Dec.

The Functional Outcome of Limb Salvage of Proximal Femur Tumors With Modular Endoprosthesis: A Prospective Study

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The Functional Outcome of Limb Salvage of Proximal Femur Tumors With Modular Endoprosthesis: A Prospective Study

Hiranya Kumar et al. Cureus. .

Abstract

Introduction The proximal femur is a common site for primary bone sarcomas, including Ewing's sarcoma, chondrosarcoma, osteosarcoma, and giant cell tumors (GCT). Extensive resections are challenging to reconstruct because the size of the tumor may necessitate an extensive resection of the femur to achieve adequate oncologic clearance. The resection of the proximal femur can result in hip joint instability due to the loss of the strong native hip capsule or hip abductor strength. With a wide range of reconstruction options, such as resection arthrodesis, allograft-prosthetic composite (APC), and endoprosthesis, we can achieve limb salvage with good functional outcomes. Objective The objective of this case series is to evaluate the clinical outcomes and complications associated with endoprosthesis replacement in patients with proximal femur tumors. Methods A prospective analysis was conducted with 32 patients who underwent modular endoprosthesis replacement for proximal femoral tumors at our institution. Patient data, tumor characteristics, surgical details, and postoperative outcomes were collected and analyzed. Results The study involved 32 patients who met the inclusion criteria. They were assessed using the Musculoskeletal Tumor Society Score (MSTS), which showed good functional outcomes in 72.84% of the patients. The study highlights the functional outcomes and potential complications associated with the use of modular prostheses. Conclusion Endoprosthesis replacement in proximal femur tumors is a viable treatment option, providing good functional outcomes and an acceptable method for limb salvage, which enhances the quality of life.

Keywords: bone tumor and limb salvage; functional outcome; modular endoprosthesis; msts; proximal femur tumors.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Graphical Representation of the Results of Musculoskeletal Tumor Society Score Assessment.
Figure 2
Figure 2. A Case of a 38-Year-Old Male With Recurrent GCT of the Right Proximal Femur.
GCT: giant cell tumor
Figure 3
Figure 3. A Case of a 43-Year-Old Female With Fibrous Dysplasia of the Right Proximal Femur.
Figure 4
Figure 4. A Case of a 41-Year-Old Female Diagnosed With Metastasis Secondary to Carcinoma of the Thyroid.
Figure 5
Figure 5. A Case of a 23-Year-Old Male With Telangiectatic Osteosarcoma.

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References

    1. Bickels J, Meller I, Henshaw R, Malawer M. Musculoskeletal cancer surgery. Dordrecht, Netherlands: Springer; 2004. Proximal and total femur resection with endoprosthetic reconstruction; pp. 439–458.
    1. Functional outcome of endoprosthetic proximal femoral replacement. Ogilvie CM, Wunder JS, Ferguson PC, Griffin AM, Bell RS. Clin Orthop Relat Res. 2004:44–48. - PubMed
    1. Salvage of the proximal femur following pathological fractures involving benign bone tumors. Carvallo PI, Griffin AM, Ferguson PC, Wunder JS. J Surg Oncol. 2015;112:846–852. - PubMed
    1. Staging of bone tumors: a review with illustrative examples. Stacy GS, Mahal RS, Peabody TD. AJR Am J Roentgenol. 2006;186:967–976. - PubMed
    1. A system for the functional evaluation of reconstructive procedures after surgical treatment of tumors of the musculoskeletal system. Enneking WF, Dunham W, Gebhardt MC, Malawar M, Pritchard DJ. https://pubmed.ncbi.nlm.nih.gov/8425352/ Clin Orthop Relat Res. 1993:241–246. - PubMed

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