Management of locally advanced adenocarcinoma of the oesophagus and oesophagogastric junction: the Neo-AEGIS trial

Affiliations

¹ Department of Oesophagogastric Surgery, Norfolk and Norwich University Hospital NHS Trust, Norwich, NR4 7UY, UK; University of East Anglia, Norwich Medical School, Norwich, UK. Electronic address: sri.sivarajan@nnuh.nhs.uk.
² Department of Oesophagogastric Surgery, Norfolk and Norwich University Hospital NHS Trust, Norwich, NR4 7UY, UK.
³ Department of Oncology, Queen Elizabeth Hospital, King's Lynn, UK.
⁴ Department of Oncology, Norfolk and Norwich University Hospital NHS Trust, Norwich, NR4 7UY, UK.
⁵ Department of Oesophagogastric Surgery, Norfolk and Norwich University Hospital NHS Trust, Norwich, NR4 7UY, UK; University of East Anglia, Norwich Medical School, Norwich, UK.

Comment

Sri Sivarajan et al. Lancet Gastroenterol Hepatol. 2024 Feb.

. 2024 Feb;9(2):102.

doi: 10.1016/S2468-1253(23)00375-8.

¹ Department of Oesophagogastric Surgery, Norfolk and Norwich University Hospital NHS Trust, Norwich, NR4 7UY, UK; University of East Anglia, Norwich Medical School, Norwich, UK. Electronic address: sri.sivarajan@nnuh.nhs.uk.
² Department of Oesophagogastric Surgery, Norfolk and Norwich University Hospital NHS Trust, Norwich, NR4 7UY, UK.
³ Department of Oncology, Queen Elizabeth Hospital, King's Lynn, UK.
⁴ Department of Oncology, Norfolk and Norwich University Hospital NHS Trust, Norwich, NR4 7UY, UK.
⁵ Department of Oesophagogastric Surgery, Norfolk and Norwich University Hospital NHS Trust, Norwich, NR4 7UY, UK; University of East Anglia, Norwich Medical School, Norwich, UK.

No abstract available

Conflict of interest statement

We declare no competing interests.

Trimodality therapy versus perioperative chemotherapy in the management of locally advanced adenocarcinoma of the oesophagus and oesophagogastric junction (Neo-AEGIS): an open-label, randomised, phase 3 trial.
Reynolds JV, Preston SR, O'Neill B, Lowery MA, Baeksgaard L, Crosby T, Cunningham M, Cuffe S, Griffiths GO, Parker I, Risumlund SL, Roy R, Falk S, Hanna GB, Bartlett FR, Alvarez-Iglesias A, Achiam MP, Nilsson M, Piessen G, Ravi N, O'Toole D, Johnston C, McDermott RS, Turkington RC, Wahed S, Sothi S, Ford H, Wadley MS, Power D; Neo-AEGIS Investigators and Trial Group. Reynolds JV, et al. Lancet Gastroenterol Hepatol. 2023 Nov;8(11):1015-1027. doi: 10.1016/S2468-1253(23)00243-1. Epub 2023 Sep 18. Lancet Gastroenterol Hepatol. 2023. PMID: 37734399 Free PMC article. Clinical Trial.