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. 2023 Jul-Dec;13(2):79-83.
doi: 10.5005/jp-journals-10018-1406.

Depression among Patients with Chronic Hepatitis B: A Cross-sectional Study in a Tertiary Hospital of Bangladesh

Merina Rahman  1 , Sheikh Mohammad Noor-E-Alam  2 , Md Abdur Rahim  2 , Dulal Chandra Das  2 , Faysal Ahmed  2 , Ayub Al Mamun  2 , Tasnim Mahmud  3 , Tarim Mahmood  4
Affiliations

Depression among Patients with Chronic Hepatitis B: A Cross-sectional Study in a Tertiary Hospital of Bangladesh

Merina Rahman et al. Euroasian J Hepatogastroenterol. 2023 Jul-Dec.

Abstract

Background: Patients with chronic hepatitis B suffer not only from physical illness. Rather, they often present with the mental health consequences of this chronic disease.

Objective: The major objective was to assess the level of depression among patients having chronic hepatitis B.

Method: The Department of Hepatology of Bangabandhu Sheikh Mujib Medical University directed this study which was a comparative cross-sectional study during time duration from September 2021 to September 2022. Incidence and grading of depression between patients with chronic hepatitis B and HBsAg negative healthy volunteers were assessed and compared through this study. The association of different variables with depression among chronic hepatitis B (CHB) patients was also measured.

Results: Out of 90 patients having chronic hepatitis B, 52 (57.8%) were found to have some degree of depression; whereas among 90 HBsAg-negative healthy controls, 32 (35.6%) were found to have various degrees of depression. The dissimilarity between the two groups was significantly determined (p-value < 0.05). The majority of the depressed population from both groups had mild degrees of depression, however, the variance was not top the notch (p-value > 0.05). But the prevalence of moderate depression and moderately severe depression was statistically significant among CHB patients compared to their counterpart controls. Depression among CHB patients was found to be female-predominant.

Conclusion: The study has shown a higher prevalence of depression among patients with chronic hepatitis B compared to HBsAg-negative healthy controls.

How to cite this article: Rahman M, Noor-E-Alam SM, Rahim MA, et al. Depression among Patients with Chronic Hepatitis B: A Cross-sectional Study in a Tertiary Hospital of Bangladesh. Euroasian J Hepato-Gastroenterol 2023;13(2):79-83.

Keywords: Depression; Hepatitis B; Mental health; Patient.

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Conflict of interest statement

Source of support: Nil Conflict of interest: Dr Sheikh Mohammad Noor-E-Alam, Dr Md Abdur Rahim are associated as the Editorial Board Members of this journal and this manuscript was subjected to this journal's standard review procedures, with this peer review handled independently of these Editorial Board Members and their research group.

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