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. 2024 Jan 3;14(1):1303-1307.
doi: 10.21037/qims-23-1072. Epub 2023 Dec 18.

Nonoperative relief of dyspnea due to mediastinal mass

Haozhong Huang #  1 , Tan Yang #  1 , Yongmei Nie  1 , Fengxu Yu  1
Affiliations

Nonoperative relief of dyspnea due to mediastinal mass

Haozhong Huang et al. Quant Imaging Med Surg. .
No abstract available

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Conflict of interest statement

Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at https://qims.amegroups.com/article/view/10.21037/qims-23-1072/coif). The authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
Comparison of imaging data of patients before and after treatment. (A) Prior to treatment, the mediastinal width of the patient’s chest radiographs was significantly wider than that of normal individuals, and the red arrows on both sides of the mediastinum indicated the development of mediastinal masses. (B) X-ray examination of the patient’s chest after treatment revealed that the width of the mediastinum had decreased significantly compared to that before treatment, and the red arrows on both sides of the mediastinum indicated the development of mediastinal masses. (C) Prior to treatment, a plain CT scan of the patient’s chest revealed a huge space-occupying lesion in the anterior mediastinum, with a maximum cross section of about 15.0 cm × 20.0 cm. The mass severely compressed the main bronchus above the bifurcation of the left and right main bronchus, and the narrowest part of the main bronchus was only about 2 mm × 3 mm (indicated by the white arrow). (D) After treatment, plain CT scan of the patient’s chest showed that the mediastinal mass had been greatly reduced, and the diameter of the main bronchus originally oppressed by the mass had almost returned to normal level (indicated by the white arrow). (E) On the third day after treatment, the patient’s PET-CT examination showed that the mediastinal mass had been significantly reduced, with a maximum cross section of 3.8 cm × 5.3 cm, and the inner diameter of the main bronchus under pressure had almost returned to normal. PET, positron emission tomography; CT, computed tomography.
Figure 2
Figure 2
Results of lymphoid histopathology and bone marrow examination of the patient. (A) The size of the lymph nodes obtained is shown, with a maximum diameter of 1.9 cm. Scale bar: 100 µm. (B,C) Immunohistochemical analysis of lymph node tissue. FISH: EBER (−). Scale bar: 100 µm. (D) Bone marrow puncture was performed with reticular fiber staining. Scale bar: 20 µm. (E,F) Immunohistochemical analysis of bone marrow. Scale: 20 µm. PAX5, paired box 5; Bcl-2, B cell lymphoma 2; BCL-6, B-cell lymphoma 6; MUM1, multiple myeloma oncogene 1; c-Myc, cellular-myelocytomatosis viral oncogene; TdT, terminal deoxynucleotidyl transferase; FISH, fluorescence in situ hybridization; EBER, Epstein–Barr early RNA; MPO, myeloperoxidase.
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