The Potential Value of Prehabilitation for Preventing Delirium in Elective Surgery for Aneurysms of the Abdominal Aorta
- PMID: 38223137
- PMCID: PMC10787545
- DOI: 10.2147/CIA.S420861
The Potential Value of Prehabilitation for Preventing Delirium in Elective Surgery for Aneurysms of the Abdominal Aorta
Erratum in
-
Erratum: The Potential Value of Prehabilitation for Preventing Delirium in Elective Surgery for Aneurysms of the Abdominal Aorta [Corrigendum].Clin Interv Aging. 2025 Jul 3;20:983-984. doi: 10.2147/CIA.S544931. eCollection 2025. Clin Interv Aging. 2025. PMID: 40630802 Free PMC article.
Abstract
Objective: Delirium is a common and serious postoperative complication in elderly patients undergoing abdominal aortic aneurysm (AAA) repair and is associated with a variety of adverse outcomes. Multimodal prehabilitation aims to identify and minimize potential risk factors for delirium and improve overall health. The aim of this study is to investigate the effect of multimodal prehabilitation on delirium incidence in elderly patients undergoing elective repair for AAA.
Methods: A single-centre cohort analysis was performed in the Netherlands for patients aged ≥70 years, undergoing elective repair for AAA (open surgery and endovascular aortic repair). Prehabilitation was gradually introduced between 2016 and 2019 and offered as standard care from 2019. The program was constructed to optimize overall health and included delirium risk assessment, home-based tailor-made exercises by a physical therapist, nutritional optimization by a dietician, iron infusion in case of anaemia and a comprehensive geriatric assessment by a geriatrician in case of frailty. The primary outcome was incidence of delirium within 30 days after surgery.
Results: A total of 81 control and 123 prehabilitation patients were included. A reduction in incidence of delirium was found (11.1% in the control group to 4.9% in the prehabilitation group), with too small numbers to reach statistical significance (p=0.09). Also, patients in the prehabilitation group had a small, non-significant decreased length of hospital stay (4 days) compared to the control group (5 days) (p=0.07).
Conclusion: Although no significant differences were found, we carefully conclude that this study provides some support for implementing multimodal prehabilitation for delirium prevention in elderly patients undergoing AAA repair. Further research with larger cohorts is necessary to identify and select patients that would most benefit from prehabilitation.
Keywords: aneurysm of the abdominal aorta; delirium; delirium/prevention and control; prehabilitation; preoperative rehabilitation.
© 2024 Meulenbroek et al.
Conflict of interest statement
The authors report no conflicts of interest in this work.
References
-
- Morisaki K, Matsubara Y, Kurose S, et al. Analysis of prognostic factors for postoperative complications and reinterventions after open surgical repair and endovascular aneurysm repair in patients with abdominal aortic aneurysm. Ann Vasc Surg. 2021;77:172–181. doi: 10.1016/j.avsg.2021.05.018 - DOI - PubMed
-
- Janssen TL, Steyerberg EW, Langenberg JCM, et al. Multimodal prehabilitation to reduce the incidence of delirium and other adverse events in elderly patients undergoing elective major abdominal surgery: an uncontrolled before-and-after study. PLoS One. 2019;14(6):e0218152. doi: 10.1371/journal.pone.0218152 - DOI - PMC - PubMed
-
- Janssen TL, Mosk CA, van Hoof-de Lepper C, et al. A multicomponent prehabilitation pathway to reduce the incidence of delirium in elderly patients in need of major abdominal surgery: study protocol for a before-and-after study. BMC Geriatr. 2019;19(1):87. doi: 10.1186/s12877-019-1101-7 - DOI - PMC - PubMed
MeSH terms
LinkOut - more resources
Full Text Sources
Medical