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Clinical Trial
. 1987 Jan;28(1):69-75.
doi: 10.1016/0304-3959(87)91061-X.

Intravenous lidocaine infusion--a new treatment of chronic painful diabetic neuropathy?

Jens Kastrup  1 , Palle Petersen, Anders Dejgård, Helle R Angelo, Jannik Hilsted
Affiliations
Clinical Trial

Intravenous lidocaine infusion--a new treatment of chronic painful diabetic neuropathy?

Jens Kastrup et al. Pain. 1987 Jan.

Abstract

In a randomized double-blind, cross-over study the effect of intravenous lidocaine (5 mg/kg body weight) on the symptoms and signs of painful diabetic neuropathy of more than 6 months duration has been evaluated. Using a clinical symptom scale, there was significant beneficial effect 1 and 8 days after lidocaine infusion compared to after saline infusion (P less than 0.05 and P less than 0.02, respectively). The duration of the individual effect ranged from 3 to 21 days. Lidocaine infusion had no effect on the objective measurements of neuropathy. Intravenous lidocaine infusion seems to be a new alternative treatment of chronic painful diabetic neuropathy.

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