Author Correction: A genomic mutational constraint map using variation in 76,156 human genomes

Siwei Chen^#^{1

2}, Laurent C Francioli^#^{3

4}, Julia K Goodrich³, Ryan L Collins^{3

5

6}, Masahiro Kanai^{3

4}, Qingbo Wang^{3

7}, Jessica Alföldi^{3

4}, Nicholas A Watts^{3

4}, Christopher Vittal^{3

4}, Laura D Gauthier⁸, Timothy Poterba^{3

4

9}, Michael W Wilson^{3

4}, Yekaterina Tarasova³, William Phu^{3

10}, Riley Grant³, Mary T Yohannes³, Zan Koenig^{4

9}, Yossi Farjoun¹¹, Eric Banks⁸, Stacey Donnelly¹², Stacey Gabriel¹³, Namrata Gupta^{3

13}, Steven Ferriera¹³, Charlotte Tolonen⁸, Sam Novod⁸, Louis Bergelson⁸, David Roazen⁸, Valentin Ruano-Rubio⁸, Miguel Covarrubias⁸, Christopher Llanwarne⁸, Nikelle Petrillo⁸, Gordon Wade⁸, Thibault Jeandet⁸, Ruchi Munshi⁸, Kathleen Tibbetts⁸; Genome Aggregation Database Consortium; Anne O'Donnell-Luria^{3

5

10}, Matthew Solomonson^{3

4}, Cotton Seed^{4

9}, Alicia R Martin^{3

4

9}, Michael E Talkowski^{3

5

9}, Heidi L Rehm^{3

5}, Mark J Daly^{3

4

14}, Grace Tiao^{3

4}, Benjamin M Neale^#^{3

4}, Daniel G MacArthur^#^{3

15

16}, Konrad J Karczewski^{17

18

19}

Collaborators, Affiliations

Collaborators

Genome Aggregation Database Consortium:
Maria Abreu, Carlos A Aguilar Salinas, Tariq Ahmad, Christine M Albert, Diego Ardissino, Irina M Armean, Elizabeth G Atkinson, Gil Atzmon, John Barnard, Samantha M Baxter, Laurent Beaugerie, Emelia J Benjamin, David Benjamin, Michael Boehnke, Lori L Bonnycastle, Erwin P Bottinger, Donald W Bowden, Matthew J Bown, Harrison Brand, Steven Brant, Ted Brookings, Sam Bryant, Sarah E Calvo, Hannia Campos, John C Chambers, Juliana C Chan, Katherine R Chao, Sinéad Chapman, Daniel I Chasman, Rex Chisholm, Judy Cho, Rajiv Chowdhury, Mina K Chung, Wendy K Chung, Kristian Cibulskis, Bruce Cohen, Kristen M Connolly, Adolfo Correa, Beryl B Cummings, Dana Dabelea, John Danesh, Dawood Darbar, Phil Darnowsky, Joshua Denny, Ravindranath Duggirala, Josée Dupuis, Patrick T Ellinor, Roberto Elosua, James Emery, Eleina England, Jeanette Erdmann, Tõnu Esko, Emily Evangelista, Diane Fatkin, Jose Florez, Andre Franke, Jack Fu, Martti Färkkilä, Kiran Garimella, Jeff Gentry, Gad Getz, David C Glahn, Benjamin Glaser, Stephen J Glatt, David Goldstein, Clicerio Gonzalez, Leif Groop, Sanna Gudmundsson, Andrea Haessly, Christopher Haiman, Ira Hall, Craig L Hanis, Matthew Harms, Mikko Hiltunen, Matti M Holi, Christina M Hultman, Chaim Jalas, Mikko Kallela, Diane Kaplan, Jaakko Kaprio, Sekar Kathiresan, Eimear E Kenny, Bong-Jo Kim, Young Jin Kim, Daniel King, George Kirov, Jaspal Kooner, Seppo Koskinen, Harlan M Krumholz, Subra Kugathasan, Soo Heon Kwak, Markku Laakso, Nicole Lake, Trevyn Langsford, Kristen M Laricchia, Terho Lehtimäki, Monkol Lek, Emily Lipscomb, Ruth J F Loos, Wenhan Lu, Steven A Lubitz, Teresa Tusie Luna, Ronald C W Ma, Gregory M Marcus, Jaume Marrugat, Kari M Mattila, Steven McCarroll, Mark I McCarthy, Jacob L McCauley, Dermot McGovern, Ruth McPherson, James B Meigs, Olle Melander, Andres Metspalu, Deborah Meyers, Eric V Minikel, Braxton D Mitchell, Vamsi K Mootha, Aliya Naheed, Saman Nazarian, Peter M Nilsson, Michael C O'Donovan, Yukinori Okada, Dost Ongur, Lorena Orozco, Michael J Owen, Colin Palmer, Nicholette D Palmer, Aarno Palotie, Kyong Soo Park, Carlos Pato, Ann E Pulver, Dan Rader, Nazneen Rahman, Alex Reiner, Anne M Remes, Dan Rhodes, Stephen Rich, John D Rioux, Samuli Ripatti, Dan M Roden, Jerome I Rotter, Nareh Sahakian, Danish Saleheen, Veikko Salomaa, Andrea Saltzman, Nilesh J Samani, Kaitlin E Samocha, Alba Sanchis-Juan, Jeremiah Scharf, Molly Schleicher, Heribert Schunkert, Sebastian Schönherr, Eleanor G Seaby, Svati H Shah, Megan Shand, Ted Sharpe, Moore B Shoemaker, Tai Shyong, Edwin K Silverman, Moriel Singer-Berk, Pamela Sklar, Jonathan T Smith, J Gustav Smith, Hilkka Soininen, Harry Sokol, Rachel G Son, Jose Soto, Tim Spector, Christine Stevens, Nathan O Stitziel, Patrick F Sullivan, Jaana Suvisaari, E Shyong Tai, Kent D Taylor, Yik Ying Teo, Ming Tsuang, Tiinamaija Tuomi, Dan Turner, Teresa Tusie-Luna, Erkki Vartiainen, Marquis Vawter, Lily Wang, Arcturus Wang, James S Ware, Hugh Watkins, Rinse K Weersma, Ben Weisburd, Maija Wessman, Nicola Whiffin, James G Wilson, Ramnik J Xavier

Affiliations

¹ Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA. siwei@broadinstitute.org.
² Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA. siwei@broadinstitute.org.
³ Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
⁴ Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.
⁵ Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
⁶ Division of Medical Sciences, Harvard Medical School, Boston, MA, USA.
⁷ Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.
⁸ Data Science Platform, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
⁹ Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
¹⁰ Division of Genetics and Genomics, Boston Children's Hospital, Boston, MA, USA.
¹¹ Richards Lab, Lady Davis Institute, Montreal, Quebec, Canada.
¹² Broad Institute of MIT and Harvard, Cambridge, MA, USA.
¹³ Broad Genomics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
¹⁴ Institute for Molecular Medicine Finland (FIMM), Helsinki, Finland.
¹⁵ Centre for Population Genomics, Garvan Institute of Medical Research and UNSW Sydney, Sydney, New South Wales, Australia.
¹⁶ Centre for Population Genomics, Murdoch Children's Research Institute, Melbourne, Victoria, Australia.
¹⁷ Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA. konradk@broadinstitute.org.
¹⁸ Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA. konradk@broadinstitute.org.
¹⁹ Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA. konradk@broadinstitute.org.

^# Contributed equally.

PMID: 38225470
DOI: 10.1038/s41586-024-07050-7

Published Erratum

Author Correction: A genomic mutational constraint map using variation in 76,156 human genomes

Siwei Chen et al. Nature. 2024 Feb.

. 2024 Feb;626(7997):E1.

doi: 10.1038/s41586-024-07050-7.

Authors

Collaborators

Genome Aggregation Database Consortium:
Maria Abreu, Carlos A Aguilar Salinas, Tariq Ahmad, Christine M Albert, Diego Ardissino, Irina M Armean, Elizabeth G Atkinson, Gil Atzmon, John Barnard, Samantha M Baxter, Laurent Beaugerie, Emelia J Benjamin, David Benjamin, Michael Boehnke, Lori L Bonnycastle, Erwin P Bottinger, Donald W Bowden, Matthew J Bown, Harrison Brand, Steven Brant, Ted Brookings, Sam Bryant, Sarah E Calvo, Hannia Campos, John C Chambers, Juliana C Chan, Katherine R Chao, Sinéad Chapman, Daniel I Chasman, Rex Chisholm, Judy Cho, Rajiv Chowdhury, Mina K Chung, Wendy K Chung, Kristian Cibulskis, Bruce Cohen, Kristen M Connolly, Adolfo Correa, Beryl B Cummings, Dana Dabelea, John Danesh, Dawood Darbar, Phil Darnowsky, Joshua Denny, Ravindranath Duggirala, Josée Dupuis, Patrick T Ellinor, Roberto Elosua, James Emery, Eleina England, Jeanette Erdmann, Tõnu Esko, Emily Evangelista, Diane Fatkin, Jose Florez, Andre Franke, Jack Fu, Martti Färkkilä, Kiran Garimella, Jeff Gentry, Gad Getz, David C Glahn, Benjamin Glaser, Stephen J Glatt, David Goldstein, Clicerio Gonzalez, Leif Groop, Sanna Gudmundsson, Andrea Haessly, Christopher Haiman, Ira Hall, Craig L Hanis, Matthew Harms, Mikko Hiltunen, Matti M Holi, Christina M Hultman, Chaim Jalas, Mikko Kallela, Diane Kaplan, Jaakko Kaprio, Sekar Kathiresan, Eimear E Kenny, Bong-Jo Kim, Young Jin Kim, Daniel King, George Kirov, Jaspal Kooner, Seppo Koskinen, Harlan M Krumholz, Subra Kugathasan, Soo Heon Kwak, Markku Laakso, Nicole Lake, Trevyn Langsford, Kristen M Laricchia, Terho Lehtimäki, Monkol Lek, Emily Lipscomb, Ruth J F Loos, Wenhan Lu, Steven A Lubitz, Teresa Tusie Luna, Ronald C W Ma, Gregory M Marcus, Jaume Marrugat, Kari M Mattila, Steven McCarroll, Mark I McCarthy, Jacob L McCauley, Dermot McGovern, Ruth McPherson, James B Meigs, Olle Melander, Andres Metspalu, Deborah Meyers, Eric V Minikel, Braxton D Mitchell, Vamsi K Mootha, Aliya Naheed, Saman Nazarian, Peter M Nilsson, Michael C O'Donovan, Yukinori Okada, Dost Ongur, Lorena Orozco, Michael J Owen, Colin Palmer, Nicholette D Palmer, Aarno Palotie, Kyong Soo Park, Carlos Pato, Ann E Pulver, Dan Rader, Nazneen Rahman, Alex Reiner, Anne M Remes, Dan Rhodes, Stephen Rich, John D Rioux, Samuli Ripatti, Dan M Roden, Jerome I Rotter, Nareh Sahakian, Danish Saleheen, Veikko Salomaa, Andrea Saltzman, Nilesh J Samani, Kaitlin E Samocha, Alba Sanchis-Juan, Jeremiah Scharf, Molly Schleicher, Heribert Schunkert, Sebastian Schönherr, Eleanor G Seaby, Svati H Shah, Megan Shand, Ted Sharpe, Moore B Shoemaker, Tai Shyong, Edwin K Silverman, Moriel Singer-Berk, Pamela Sklar, Jonathan T Smith, J Gustav Smith, Hilkka Soininen, Harry Sokol, Rachel G Son, Jose Soto, Tim Spector, Christine Stevens, Nathan O Stitziel, Patrick F Sullivan, Jaana Suvisaari, E Shyong Tai, Kent D Taylor, Yik Ying Teo, Ming Tsuang, Tiinamaija Tuomi, Dan Turner, Teresa Tusie-Luna, Erkki Vartiainen, Marquis Vawter, Lily Wang, Arcturus Wang, James S Ware, Hugh Watkins, Rinse K Weersma, Ben Weisburd, Maija Wessman, Nicola Whiffin, James G Wilson, Ramnik J Xavier

Affiliations

¹ Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA. siwei@broadinstitute.org.
² Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA. siwei@broadinstitute.org.
³ Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
⁴ Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.
⁵ Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
⁶ Division of Medical Sciences, Harvard Medical School, Boston, MA, USA.
⁷ Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.
⁸ Data Science Platform, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
⁹ Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
¹⁰ Division of Genetics and Genomics, Boston Children's Hospital, Boston, MA, USA.
¹¹ Richards Lab, Lady Davis Institute, Montreal, Quebec, Canada.
¹² Broad Institute of MIT and Harvard, Cambridge, MA, USA.
¹³ Broad Genomics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
¹⁴ Institute for Molecular Medicine Finland (FIMM), Helsinki, Finland.
¹⁵ Centre for Population Genomics, Garvan Institute of Medical Research and UNSW Sydney, Sydney, New South Wales, Australia.
¹⁶ Centre for Population Genomics, Murdoch Children's Research Institute, Melbourne, Victoria, Australia.
¹⁷ Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA. konradk@broadinstitute.org.
¹⁸ Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA. konradk@broadinstitute.org.
¹⁹ Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA. konradk@broadinstitute.org.

^# Contributed equally.

PMID: 38225470
DOI: 10.1038/s41586-024-07050-7

No abstract available

PubMed Disclaimer

Erratum for

A genomic mutational constraint map using variation in 76,156 human genomes.
Chen S, Francioli LC, Goodrich JK, Collins RL, Kanai M, Wang Q, Alföldi J, Watts NA, Vittal C, Gauthier LD, Poterba T, Wilson MW, Tarasova Y, Phu W, Grant R, Yohannes MT, Koenig Z, Farjoun Y, Banks E, Donnelly S, Gabriel S, Gupta N, Ferriera S, Tolonen C, Novod S, Bergelson L, Roazen D, Ruano-Rubio V, Covarrubias M, Llanwarne C, Petrillo N, Wade G, Jeandet T, Munshi R, Tibbetts K; Genome Aggregation Database Consortium; O'Donnell-Luria A, Solomonson M, Seed C, Martin AR, Talkowski ME, Rehm HL, Daly MJ, Tiao G, Neale BM, MacArthur DG, Karczewski KJ. Chen S, et al. Nature. 2024 Jan;625(7993):92-100. doi: 10.1038/s41586-023-06045-0. Epub 2023 Dec 6. Nature. 2024. PMID: 38057664 Free PMC article.

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Author Correction: A genomic mutational constraint map using variation in 76,156 human genomes

Collaborators

Affiliations

Author Correction: A genomic mutational constraint map using variation in 76,156 human genomes

Authors

Collaborators

Affiliations

Erratum for

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Grants and funding

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