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Review
. 2024 Mar;35(3):511-515.
doi: 10.1111/jce.16180. Epub 2024 Jan 15.

Posttransplant atrial fibrillation: Evidence of early posttransplant recipient-to-donor atrioatrial connections

Bright Izekor  1 , Christopher Perez  1 , Javier Banchs  1 , Gregory Olsovsky  1
Affiliations
Review

Posttransplant atrial fibrillation: Evidence of early posttransplant recipient-to-donor atrioatrial connections

Bright Izekor et al. J Cardiovasc Electrophysiol. 2024 Mar.

Abstract

Introduction: Atrial fibrillation and atrial flutter originating from the donor s heart is a commonly reported complication post heart transplant. Atrial tachyarrhythmia originating from the recipient s heart, propagated through recipient-to-donor connections, is rare with only few cases reported in the literature; most reported cases from our review occur years post-transplant.

Case: A 47-year-old male presented with atrial tachycardia 6 months post heart transplant. Electrophysiologic study demonstrated atrial fibrillation originating from native heart and propagated through atrio-atrial connections to the donor heart. This arrhythmia was successfully terminated with radiofrequency ablation.

Conclusion: Atrio-atrial connection between recipient and donor can form as early as a few months post heart transplant. Radiofrequency ablation appears to be an effective treatment for atrial fibrillation propagated through donor-to-recipient connections.

Keywords: ablation; atrial fibrillation; atrial tachycardia; heart transplant; mapping; radiofrequency.

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References

REFERENCES

    1. Jacquet L, Ziady G, Stein K, et al. Cardiac rhythm disturbances early after orthotopic heart transplantation: prevalence and clinical importance of the observed abnormalities. J Am Coll Cardiol. 1990;16(4):832-837. doi:10.1016/s0735-1097(10)80330-4
    1. Thajudeen A, Stecker EC, Shehata M, et al. Arrhythmias after heart transplantation: mechanisms and management. J Am Heart Assoc. 2012;1(2):e001461. doi:10.1161/JAHA.112.001461
    1. Russo MJ, Chen JM, Sorabella RA, et al. The effect of ischemic time on survival after heart transplantation varies by donor age: an analysis of the united network for organ sharing database. J Thorac Cardiovasc Surg. 2007;133(2):554-559. doi:10.1016/j.jtcvs.2006.09.019
    1. Joglar JA, Wan EY, Chung MK, et al. Management of arrhythmias after heart transplant. Circ Arrhythmia Electrophysiol. 2021;14(3):e007954. doi:10.1161/CIRCEP.120.007954
    1. Vaseghi M, Boyle NG, Kedia R, et al. Supraventricular tachycardia after orthotopic cardiac transplantation. J Am Coll Cardiol. 2008;51:2241-2249.

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