Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023;76(4):287-292.
doi: 10.5173/ceju.2023.142. Epub 2023 Sep 22.

The influence of the operator's experience on the outcomes of fusion prostate biopsy

Grzegorz Rempega  1 , Paweł Rajwa  1   2 , Jakub Ryszawy  1 , Jakub Wojnarowicz  1 , Maksymilian Kowalik  1 , Marcela Krzempek  3 , Aleksandra Krzywon  3 , Michał Dobrakowski  4   5 , Ewa Fil  6 , Bartłomiej Burzyński  7 , Andrzej Paradysz  1 , Piotr Bryniarski  1
Affiliations

The influence of the operator's experience on the outcomes of fusion prostate biopsy

Grzegorz Rempega et al. Cent European J Urol. 2023.

Abstract

Introduction: Magnetic resonance imgaing (MRI) targeted biopsy is the gold standard for prostate cancer (PCa) diagnosis. In this study, we examined the association between the operator's experience and the improvement in the precision of the MRI prostate biopsy procedure and the detection of PCa.

Material and methods: We included consecutive patients who underwent prostate fusion biopsy. Data on biopsy duration, prostate-specific antigen (PSA) value, lesion size, number of samples taken, number of cores involved, and International Society of Urological Pathology (ISUP) grade were subjected to statistical analysis, with the study group divided into three consecutive time periods (tertiles).

Results: There were statistically significant differences in biopsy duration between tertiles (p <0.001). The greatest difference in the involved/taken cores ratio occurred between the first and third tertile (p = 0.002). The difference between the first and second tertile was insignificant (p = 0.4), while the difference between the second and third tertile was statistically significant (p = 0.004). The differences between tertiles in Prostate Imaging and Reporting Data System v2.1 were also significant (p = 0.003). The PSA value (p = 0.036) was statistically significant, unlike prostate volume (p = 0.16), digital rectal examination (DRE) (p = 0.7), and ISUP grade (p = 0.7). There was no statistical difference between tested tertiles in the number of detected PCa ISUP ≥2 (Z = 0.191; p = 0.8).

Conclusions: The abilities and precision of the operator increase with the increase in the number of procedures performed. The biopsy duration is shortened, and the detection of PCa during the procedure seems to improve with the operator's experience.

Keywords: biopsy; image-guided biopsy; prostate cancer.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
Involved/taken cores ratios in the tertiles of biopsy date.
Figure 2
Figure 2
The distribution of International Society of Urological Pathology (ISUP) values in subgroups I and II (I <4 targeted cores; II ≥4 targeted cores).
See this image and copyright information in PMC

References

    1. Weinreb JC, Barentsz JO, Choyke PL, et al. PI-RADS Prostate Imaging - Reporting and Data System: 2015, Version 2. Eur Urol. 2016; 69: 16-40. - PMC - PubMed
    1. Chuang RJ, Marks LS. Targeted and Systematic Biopsy for Diagnosis and Management of Prostate Cancer. Clin Oncol. 2020; 32: 144-148. - PubMed
    1. O'Shea A, Harisinghani M. PI-RADS: multiparametric MRI in prostate cancer. MAGMA. 2022; 35: 523-532. - PubMed
    1. Rai BP, Mayerhofer C, Somani BK, Kallidonis P, Nagele U, Tokas T. Magnetic Resonance Imaging/Ultrasound Fusion-guided Transperineal Versus Magnetic Resonance Imaging/Ultrasound Fusion-guided Transrectal Prostate Biopsy-A Systematic Review. Eur Urol Oncol. 2021; 4: 904-913. - PubMed
    1. Rempega G, Rajwa P, Kępiński M, et al. The Severity of Pain in Prostate Biopsy Depends on the Biopsy Sector. J Pers Med. 2023; 13: 431. - PMC - PubMed

LinkOut - more resources