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Case Reports
. 2024 Jan;29(3):2400002.
doi: 10.2807/1560-7917.ES.2024.29.3.2400002.

A case of swine influenza A(H1N2)v in England, November 2023

Jade Cogdale  1 , Beatrix Kele  1 , Richard Myers  1 , Ruth Harvey  2 , Abi Lofts  2 , Tanya Mikaiel  2 , Katja Hoschler  1 , Ashley C Banyard  3 , Joe James  3 , Benjamin C Mollett  3   4 , Alexander Mp Byrne  3 , Jamie Lopez-Bernal  1 , Conall H Watson  1 , Meera Chand  1 , William Welfare  5 , Deborah A Williamson  1 , Isabel Oliver  1 , Simon Padfield  6 , Andrew Lee  6 , Suzanne Calvert  6 , Martin A Bewley  6 , Louise Wallace  7 , Simon deLusignan  8   9 , Nicola S Lewis  2   4 , Ian H Brown  3 , Maria Zambon  1 ; Influenza A(H1N2)v Incident Management Team  1
Affiliations
Case Reports

A case of swine influenza A(H1N2)v in England, November 2023

Jade Cogdale et al. Euro Surveill. 2024 Jan.

Erratum in

  • Authors' correction for Euro Surveill. 2024;29(3).
    Eurosurveillance editorial team. Eurosurveillance editorial team. Euro Surveill. 2024 Jan;29(4):250125c. doi: 10.2807/1560-7917.ES.2024.29.4.250125c. Euro Surveill. 2024. PMID: 38275018 Free PMC article. No abstract available.

Abstract

Under International Health Regulations from 2005, a human infection caused by a novel influenza A virus variant is considered an event that has potential for high public health impact and is immediately notifiable to the World Health Organisation. We here describe the clinical, epidemiological and virological features of a confirmed human case of swine influenza A(H1N2)v in England detected through community respiratory virus surveillance. Swabbing and contact tracing helped refine public health risk assessment, following this unusual and unexpected finding.

Keywords: England; H1N2; Influenza A; Surveillance; Swine; Zoonosis.

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Conflict of interest statement

Conflict of interest: SdeL has received vaccine related research funding at his University from AstraZeneca, GSK, Moderna, Sanofi and Seqirus. He has been a member of advisory boards for AstraZeneca, GSK, Sanofi and Seqirus with any funding paid to his University. CW’s department has received cost-recovery payments from CSL Seqirus for a regulatory analysis on seasonal influenza vaccination.

Figures

Figure 1
Figure 1
Phylogeny of global influenza A (H1) swine sequence data and the viral sequence of the case in this report, United Kingdom, November 2023
Figure 2
Figure 2
Phylogeny of influenza A(H1) 1B swine sequence data and the viral sequence of the case in this report, United Kingdom, November 2023
See this image and copyright information in PMC

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References

    1. Leston M, Elson WH, Watson C, Lakhani A, Aspden C, Bankhead CR, et al. Representativeness, vaccination uptake, and COVID-19 clinical outcomes 2020-2021 in the UK Oxford-Royal College of General Practitioners Research and Surveillance Network: cohort profile summary. JMIR Public Health Surveill. 2022;8(12):e39141. 10.2196/39141 - DOI - PMC - PubMed
    1. Gu X, Watson C, Agrawal U, Whitaker H, Elson WH, Anand S, et al. Post-pandemic development of sentinel surveillance of respiratory disease, in the context of the WHO mosaic framework: protocol for the English primary care network 2023-2024. JMIR Preprints. 30/08/2023:52047: 10.2196/preprints.52047 10.2196/preprints.52047 - DOI - DOI - PMC - PubMed
    1. Zhou B, Donnelly ME, Scholes DT, St George K, Hatta M, Kawaoka Y, et al. Single-reaction genomic amplification accelerates sequencing and vaccine production for classical and Swine origin human influenza a viruses. J Virol. 2009;83(19):10309-13. 10.1128/JVI.01109-09 - DOI - PMC - PubMed
    1. Anderson TK, Macken CA, Lewis NS, Scheuermann RH, Van Reeth K, Brown IH, et al. A phylogeny-based global nomenclature system and automated annotation tool for H1 hemagglutinin genes from swine influenza A viruses. MSphere. 2016;1(6):e00275-16. 10.1128/mSphere.00275-16 - DOI - PMC - PubMed
    1. World Health Organization (WHO). Genetic and antigenic characteristics of zoonotic influenza A viruses and development of candidate vaccine viruses for pandemic preparedness. Geneva: WHO; 2023. Available from: https://cdn.who.int/media/docs/default-source/influenza/who-influenza-re...

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