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. 2024 Mar;99(3):494-496.
doi: 10.1002/ajh.27205. Epub 2024 Jan 19.

T-cell prolymphocytic leukemia: Epidemiology and survival trends in the era of novel treatments

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Free article

T-cell prolymphocytic leukemia: Epidemiology and survival trends in the era of novel treatments

Victoria A Vardell et al. Am J Hematol. 2024 Mar.
Free article

Abstract

Survival remains poor for T-cell prolymphocytic leukemia, though treatment in recent years, associated with access to novel therapies, and management at academic medical centers is associated with improved outcomes. There remains a critical need to improve the available treatment options for this population, and access to specialized academic medical centers, comprehensive supportive care, clinical trials, and early palliative care remains essential for T-PLL patients.

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References

REFERENCES

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    1. Staber PB, Herling M, Bellido M, et al. Consensus criteria for diagnosis, staging, and treatment response assessment of T-cell prolymphocytic leukemia. Blood. 2019;134(14):1132-1143.
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    1. Jain P, Aoki E, Keating M, et al. Characteristics, outcomes, prognostic factors and treatment of patients with T-cell prolymphocytic leukemia (T-PLL). Ann Oncol. 2017;28(7):1554-1559.
    1. Braun T, Jan J, Wahnschaffe L, Herling M. Advances and perspectives in the treatment of T-PLL. Curr Hematol Malig Rep. 2020;15:113-124.

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