Enzymatic and non-enzymatic transnitrosylation: "SCAN"ning the SNO-proteome
- PMID: 38242098
- DOI: 10.1016/j.molcel.2023.12.018
Enzymatic and non-enzymatic transnitrosylation: "SCAN"ning the SNO-proteome
Abstract
In a recent study in Cell, Zhou et al.1 propose enzymatic transfer of nitric-oxide (NO)-related species from SNO-CoA to target proteins involved in insulin signaling; this function comprises an SNO-CoA-Assisted Nitrosylase (SCAN).
Copyright © 2023 Elsevier Inc. All rights reserved.
Conflict of interest statement
Declaration of interests The authors declare no competing interests.
Comment on
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An enzyme that selectively S-nitrosylates proteins to regulate insulin signaling.Cell. 2023 Dec 21;186(26):5812-5825.e21. doi: 10.1016/j.cell.2023.11.009. Epub 2023 Dec 5. Cell. 2023. PMID: 38056462 Free PMC article.
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