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Meta-Analysis
. 2024 Mar;34(3):976-984.
doi: 10.1007/s11695-023-07050-y. Epub 2024 Jan 20.

Outcomes of One-Anastomosis Gastric Bypass Conversion to Roux-en-Y Gastric Bypass for Severe Obesity: A Systematic Review and Meta-analysis

Narek Sargsyan #  1 , Bibek Das #  2 , Henry Robb  2 , Christopher Namgoong  2 , Iihan Ali  2 , Hutan Ashrafian  2 , Samer Humadi  3 , Anuja Mitra  2 , Matyas Fehervari  2   4
Affiliations
Meta-Analysis

Outcomes of One-Anastomosis Gastric Bypass Conversion to Roux-en-Y Gastric Bypass for Severe Obesity: A Systematic Review and Meta-analysis

Narek Sargsyan et al. Obes Surg. 2024 Mar.

Abstract

One-anastomosis gastric bypass (OAGB) is an effective procedure to treat severe obesity. However, conversion to Roux-en-Y gastric bypass (RYGB) is increasing. We therefore conducted a systematic review to determine the safety and efficacy associated with OAGB-RYGB conversion. A systematic search was conducted by three independent reviewers using Medline, Embase, and the Cochrane library following PRISMA guidelines. Six studies including 134 patients were selected who were undergoing OAGB-RYGB conversion. The most common indications were reflux (47.8%), malnutrition (31.3%), and inadequate weight loss (8.2%). Study outcomes demonstrated 100% resolution of bile reflux. Overall, there was medium-term weight gain of 0.61 BMI. OAGB to RYGB conversion leads to resolution of reflux symptoms. However, it is associated with weight regain, albeit this may be acceptable to patients to treat biliary reflux.

Keywords: OAGB; RYGB; Revisional Bariatric Surgery.

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Figures

Fig. 1
Fig. 1
PRISMA outcome for OAGB conversion to RYGB
Fig. 2
Fig. 2
Forest plot demonstrating changes in BMI pre and post OAGB-RYGB conversion
Fig. 3
Fig. 3
Forest plot demonstrating changes in weight pre and post RYGB conversion
Fig. 4
Fig. 4
Forest plot demonstrating bile reflux pre and post OAGB-RYGB conversion
Fig. 5
Fig. 5
Forest plot demonstrating malnutrition pre and post OAGB-RYGB conversion
Fig. 6
Fig. 6
Forest plot demonstrating the weighted mean rate of major (Clavien-Dindo grade >3) post-conversion complications
Fig. 7
Fig. 7
Forest plot demonstrating weighted mean analysis of OAGB conversion to RYGB
See this image and copyright information in PMC

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